Document Detail

Neostriatal lesions impaired rats' delayed alternation performance in a T-maze but not in a two-key operant chamber.
MedLine Citation:
PMID:  3604765     Owner:  NLM     Status:  MEDLINE    
Rats with lesions in the neostriatal region that belongs to the prefrontal system were trained in two versions of delayed alternation. They performed as proficiently as intact animals in a two-key operant chamber. The same operated rats took many more trials to reach criterion when subsequently compared with the same control group in a T-maze. This finding demonstrates that variants of delayed alternation are not equivalent for animals with lesions in the prefrontal system. Observations suggested that delayed alternation in the operant chamber may be mastered by positional mediation.
J Mogensen; I H Iversen; I Divac
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neurobiologiae experimentalis     Volume:  47     ISSN:  0065-1400     ISO Abbreviation:  Acta Neurobiol Exp (Wars)     Publication Date:  1987  
Date Detail:
Created Date:  1987-08-07     Completed Date:  1987-08-07     Revised Date:  2011-01-07    
Medline Journal Info:
Nlm Unique ID:  1246675     Medline TA:  Acta Neurobiol Exp (Wars)     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  45-54     Citation Subset:  IM    
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MeSH Terms
Brain Damage, Chronic / physiopathology*
Conditioning, Operant / physiology
Corpus Striatum / physiopathology*
Learning / physiology*
Rats, Inbred Strains
Spatial Behavior / physiology

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