Document Detail

Neospora caninum prevalence in dogs raised under different living conditions.
MedLine Citation:
PMID:  24957000     Owner:  NLM     Status:  Publisher    
Neospora caninum is an important cause of abortion in dairy cattle worldwide. Dogs are important in the epidemiology of N. caninum because they act as definitive hosts shedding oocysts in the environment. Vertical transmission of the parasite is well recognized as an important aspect of the epidemiology of the parasite but the importance of horizontal transmission has been less studied. A N. caninum competitive ELISA was used to examine serum samples from 600 dogs that were raised under 4 different living conditions. Samples from 138 dogs living on 24 dairies with a prevalence (0-70%) of anti-N. caninum antibodies in the cattle, 294 pet dogs without neurological signs, 76 from pet dogs exhibiting neurological signs, and 92 stray dogs were examined. The overall seroprevalence of N. caninum was 23.5% (95% CI=±2.99) in the 600 dogs. Significant (P<0.05) differences were observed between the 4 different populations of dogs. The number of N. caninum positive samples were: 51 (36.9%, 95% CI=±3.09) of 138 dogs from dairies, 31 (10.5%, 95% CI=±6.38) of 294 pet dogs without neurological signs, disorders, 22 (28.9%, 95% CI=±6.70) of 76 pet dogs with neurological signs, and 37 (40.2%, 95% CI=±2.83) of 92 stray dogs. Seropositivity to N. caninum in dogs from dairies was associated with a high prevalence of N. caninum antibodies in the cattle. At the 3 dairies where no dogs were present, the seroprevalence to N. caninum in the cattle was significantly lower (P<0.05) than in the 21 dairies where dogs were present. Seroprevalence was significantly higher (P<0.05) in male dogs (97 of 366; 26.5%, 95% CI=±3.40) than in female dogs (44 of 234; 18.8%, 95% CI=±5.65). Seroprevalence in dogs increased with age suggesting postnatal exposure to N. caninum infection however, this increase was not significant (P>0.05). The prevalence of N. caninum antibodies was not significantly (P>0.05) different in dogs based on breed. These findings suggest a relationship between N. caninum infection of dogs from dairies and cattle on these dairies. However, further research is required to determine what is the most important way dogs acquire infection and how to prevent dogs from shedding oocysts.
Muhammad Mudasser Nazir; Azhar Maqbool; Masood Akhtar; Mazhar Ayaz; Atif Nisar Ahmad; Kamran Ashraf; Asif Ali; Muhammad Azhar Alam; Muhammad Amjad Ali; Abdur Rauf Khalid; David S Lindsay
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-6
Journal Detail:
Title:  Veterinary parasitology     Volume:  -     ISSN:  1873-2550     ISO Abbreviation:  Vet. Parasitol.     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7602745     Medline TA:  Vet Parasitol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier B.V. All rights reserved.
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