Document Detail


Neospora caninum associated with septic peritonitis in an adult dog.
MedLine Citation:
PMID:  16783720     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 7-year-old, male neutered Rhodesian Ridgeback dog was referred to the University of California-Davis Veterinary Medical Teaching Hospital with a 4-month history of peritonitis and episodic abdominal discomfort, lethargy, and weakness. Marked abdominal distension with a prominent fluid wave was noted on physical examination. Cytologic analysis of the abdominal fluid indicated a septic exudate with mixed bacteria and many protozoal zoites. Differentials for the identity of the protozoal zoites included Toxoplasma gondii, Sarcocystis neurona, and Neospora caninum. Indirect latex agglutination antigen testing, standard indirect fluorescent antibody testing, and PCR analysis were performed to identify the zoites. The dog's serum antibody titer for N caninum tachyzoites was 1:20,480, known polysera to N caninum reacted against zoites in the abdominal fluid, and PCR analysis of the abdominal fluid was positive for the presence of a known gene of N caninum. Based on the morphologic, immunologic, and molecular findings, the zoites were identified as N caninum. It remains unclear how the tachyzoites gained access to the peritoneal cavity. To the authors' knowledge, there are no reports of free N caninum in abdominal fluid of any species.
Authors:
Tara A Holmberg; William Vernau; Ann C Melli; Patricia A Conrad
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Veterinary clinical pathology / American Society for Veterinary Clinical Pathology     Volume:  35     ISSN:  0275-6382     ISO Abbreviation:  Vet Clin Pathol     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-19     Completed Date:  2006-08-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9880575     Medline TA:  Vet Clin Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  235-8     Citation Subset:  IM    
Affiliation:
Department of Pathology, Microbiology & Immunology, School of Veterinary Medicine, University of California - Davis, CA, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Bacterial Agents / therapeutic use
Ascitic Fluid / cytology,  parasitology
Coccidiosis / parasitology,  therapy,  veterinary*
Dog Diseases / parasitology*,  therapy
Dogs
Male
Neospora / isolation & purification*
Peritonitis / parasitology,  therapy,  veterinary*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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