| Neoplastic transformation of a human hybrid cell line by alpha particles in relation to mammography X rays. | |
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MedLine Citation:
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PMID: 17145730 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The hybrid cell line CGL1 is the only cell line which allows quantitation of neoplastic transformation in human cells. Hybrid cells were exposed to 3.4 MeV alpha particles or to mammography X rays (29 kV(p)) and both survival and neoplastic cell transformation were assayed. For comparison, previously published data obtained with 200 kV(p) X rays are also included. Alpha particles were significantly more efficient than 29 kV(p) X rays in cell killing. Surprisingly, the efficiency of mammography X rays for the induction of neoplastic cell transformation was close to that observed for alpha particles. |
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Authors:
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M Frankenberg-Schwager; S Spieren; E Pralle; D Frankenberg |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-12-04 |
Journal Detail:
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Title: Radiation protection dosimetry Volume: 122 ISSN: 0144-8420 ISO Abbreviation: Radiat Prot Dosimetry Publication Date: 2006 |
Date Detail:
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Created Date: 2007-04-30 Completed Date: 2007-07-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8109958 Medline TA: Radiat Prot Dosimetry Country: England |
Other Details:
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Languages: eng Pagination: 180-4 Citation Subset: IM |
Affiliation:
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University of Goettingen, Center of Radiology, Department of Nuclear Medicine, Von-Siebold-Strasse 3, D-37075 Goettingen, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alpha Particles* Cell Line Cell Survival / radiation effects* Cell Transformation, Neoplastic / pathology*, radiation effects* Dose-Response Relationship, Radiation Hela Cells Humans Hybridomas / pathology*, radiation effects* Mammography* Radiation Dosage X-Rays |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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