Document Detail

Neonatal wellbeing after elective caesarean delivery with general, spinal, and epidural anaesthesia.
MedLine Citation:
PMID:  8495679     Owner:  NLM     Status:  MEDLINE    
A comparison was made of the acid-base and Apgar status of neonates following general (n = 34), spinal (n = 28) and epidural (n = 23) anaesthesia for elective caesarean section. Neonates delivered following spinal anaesthesia were more acidaemic (pH = 7.249) (P < 0.05) than those delivered following epidural (pH = 7.291) or general anaesthesia (pH = 7.296) despite measures taken to minimize hypotension. The percentage of neonates with a 1 min Apgar score > or = 7 was 96% after epidural anaesthesia, 93% after spinal anaesthesia and 75% after general anaesthesia. The difference between epidural and general anaesthesia was significant (P < 0.05). Using these two measures of neonatal wellbeing, epidural anaesthesia provided the most favourable outcome.
F M Ratcliffe; J M Evans
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of anaesthesiology     Volume:  10     ISSN:  0265-0215     ISO Abbreviation:  Eur J Anaesthesiol     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-06-21     Completed Date:  1993-06-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8411711     Medline TA:  Eur J Anaesthesiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  175-81     Citation Subset:  IM    
Nuffield Department of Anaesthetics, John Radcliffe Hospital, Headington, Oxford, UK.
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MeSH Terms
Acid-Base Equilibrium / physiology*
Acidosis / blood
Anesthesia, Epidural* / methods
Anesthesia, General* / methods
Anesthesia, Obstetrical* / methods
Anesthesia, Spinal* / methods
Apgar Score*
Blood Pressure / physiology
Carbon Dioxide / blood
Cesarean Section*
Fetal Blood / chemistry
Hydrogen-Ion Concentration
Hypotension / prevention & control
Infant, Newborn / physiology*
Oxygen / blood
Prospective Studies
Umbilical Arteries
Umbilical Veins
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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