Document Detail

Neonatal tetanus in babies of women immunized with tetanus toxoid during pregnancy.
MedLine Citation:
PMID:  2284666     Owner:  NLM     Status:  MEDLINE    
In a study of 52 cases of neonatal tetanus admitted to Wesley Guild Hospital, Ilesha, it was found that 17 (33%) of the babies were delivered to mothers who had received adequate tetanus toxoid immunization during pregnancy. The 17 babies were compared with the remaining 35 babies whose mothers had not received tetanus prophylaxis. The case fatality rates in these two groups were 12.5% and 60% respectively (P less than 0.01). This report shows that neonatal tetanus can occur in babies of mothers who were immunized with tetanus toxoid during pregnancy. Maternal immunity may, however, improve the prognosis in such infants.
J A Owa; O O Makinde
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Tropical doctor     Volume:  20     ISSN:  0049-4755     ISO Abbreviation:  Trop Doct     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1991-03-18     Completed Date:  1991-03-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1301706     Medline TA:  Trop Doct     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  156-7     Citation Subset:  IM; J    
Department of Paediatrics and Child Health, Faculty of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
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MeSH Terms
Immunity, Maternally-Acquired
Infant, Newborn
Pregnancy Complications, Infectious / prevention & control
Tetanus / etiology*,  mortality,  prevention & control
Tetanus Toxoid / adverse effects*
Reg. No./Substance:
0/Tetanus Toxoid

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