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Neonatal systemic juvenile xanthogranuloma with an ominous presentation and successful treatment.
MedLine Citation:
PMID:  21695102     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
This case report originated from a case of neonatal multisystemic juvenile xanthogranuloma (JXG). The patient presented with blue muffin rush, cervical mass, bone destruction, lung nodule, hepatosplenomegaly, and coagulopathy and was successfully treated with Langerhans cell histiocytosis (LCH) based chemotherapy treatment. Similar cases in literature were reviewed and it seems that JXG, a relatively benign entity, when presented in its systemic form with liver involvement, could have an aggressive course and portend quite poor prognosis. Challenges and special consideration of the diagnosis, treatment, and future case observation are discussed.
Authors:
Rong Fan; Jihong Sun
Publication Detail:
Type:  Journal Article     Date:  2011-05-22
Journal Detail:
Title:  Clinical Medicine Insights. Oncology     Volume:  5     ISSN:  1179-5549     ISO Abbreviation:  Clin Med Insights Oncol     Publication Date:  2011  
Date Detail:
Created Date:  2011-06-22     Completed Date:  2011-07-14     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  101525771     Medline TA:  Clin Med Insights Oncol     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  157-61     Citation Subset:  -    
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