Document Detail


Neonatal septicaemia in an African city of high altitude.
MedLine Citation:
PMID:  1527816     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ninety-nine cases of neonatal septicaemia prospectively seen over a 3-year period in a large cosmopolitan African city of high altitude is presented. An incidence of 6.5 per 1000 live births was noted. Though the most important pathogens were Klebsiella spp. and Staphylococcus aureus, Citrobacter difficile and Alkalegenes faecalis were the pathogens associated with a high mortality rate. Low birth weight infants were significantly more affected. The overall mortality rate was 27.3 per cent. The commonest predisposing perinatal factors were birth asphyxia and prolonged rupture of fetal membranes. On the basis of the trend of organisms isolated and their sensitivity pattern, it is suggested that the initial use of gentamicin alone is satisfactory.
Authors:
A I Airede
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of tropical pediatrics     Volume:  38     ISSN:  0142-6338     ISO Abbreviation:  J. Trop. Pediatr.     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-10-22     Completed Date:  1992-10-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8010948     Medline TA:  J Trop Pediatr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  189-91     Citation Subset:  IM    
Affiliation:
Jos University Teaching Hospital, Murtala Mohammed Way, Nigeria.
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MeSH Terms
Descriptor/Qualifier:
Africa
Alcaligenes / isolation & purification
Altitude*
Citrobacter / isolation & purification
Cloxacillin / therapeutic use
Drug Resistance, Microbial
Female
Gentamicins / therapeutic use
Gram-Negative Bacteria / drug effects,  isolation & purification*
Gram-Positive Bacteria / drug effects,  isolation & purification*
Humans
Infant, Newborn
Klebsiella / isolation & purification
Male
Sepsis / drug therapy,  microbiology*,  mortality
Staphylococcus aureus / isolation & purification
Chemical
Reg. No./Substance:
0/Gentamicins; 61-72-3/Cloxacillin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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