Document Detail

Neonatal sepsis and meningitis caused by Neisseria meningitidis: a case report.
MedLine Citation:
PMID:  17625698     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To report a full-term newborn infant that developed a sepsis associated to meningitis caused by Neisseria meningitidis serogroup C on the 14th day of life.
CASE DESCRIPTION: The patient was a term female infant, born to a mother with Systemic Lupus Erythematosus, with birth weight of 2,610 g, Apgar Score 1, 4 and 8, who needed mechanical ventilation for 24 hours. On the 7th day of life, the neonate was discharged from the hospital with good overall condition. On the 15th day of life, the newborn infant presented fever and respiratory failure. The cerebrospinal fluid showed 1042 cells/mm3, with neutrophilic predominance, protein of 435 mg/dL, and glucose < 10 mg/dL. The blood and the cerebrospinal fluid cultures were positive for Neisseria meningitidis serogroup C. The neonate was hospitalized, needing mechanical ventilation and vasoactive drugs, and received 21 days of crystalline penicillin. After hospital discharge, there were no signs of neurological sequels and the infant was able to be breastfed. The case report presents a unique situation: an uncommon etiology of neonatal meningitis and favorable evolution, despite neurological sequels reported in the literature. This report emphasizes the need to prevent the premature exposure of newborn infants to pathological agents, especially if they presented birth injuries and/or are preterm, due to their lack of immunological capacity.
Mário Cícero Falcão; Samantha Brasil de Andrade; Maria Esther Jurfest Rivero Ceccon; Flávio Adolfo Costa Vaz
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Revista do Instituto de Medicina Tropical de São Paulo     Volume:  49     ISSN:  0036-4665     ISO Abbreviation:  Rev. Inst. Med. Trop. Sao Paulo     Publication Date:    2007 May-Jun
Date Detail:
Created Date:  2007-07-12     Completed Date:  2007-12-20     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  7507484     Medline TA:  Rev Inst Med Trop Sao Paulo     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  191-4     Citation Subset:  IM    
Faculdade de Medicina da Universidade de São Paulo, UCINE, SP, Brazil.
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MeSH Terms
Infant, Newborn
Meningitis, Meningococcal / diagnosis*,  drug therapy
Neisseria meningitidis, Serogroup C / isolation & purification*
Penicillins / therapeutic use
Sepsis / diagnosis,  drug therapy,  microbiology*
Reg. No./Substance:

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