Document Detail

Neonatal seizures: the Dublin Collaborative Study.
MedLine Citation:
PMID:  3178266     Owner:  NLM     Status:  MEDLINE    
Asphyxial seizures occurred in 89 of 101,829 infants born alive at term (0.87/1000) in three large maternity hospitals from January 1980 to December 1984. These seizures were significantly associated with antenatal complications, primiparity, and prolonged pregnancy. Meconium staining of the amniotic fluid was also associated with asphyxial seizures, but there were high false positive (11%) and false negative (50%) rates. Fifteen of the infants who had seizures died (18%) and 21 (25%) were handicapped at 1 year. Outcome was most successfully predicted by the way the infant was feeding at 1-2 weeks. All infants taking more than half their estimated requirements by mouth at 1 week were normal, and those still being fed by tube at 2 weeks were handicapped.
P D Curtis; T G Matthews; T A Clarke; M Darling; P Crowley; E Griffin; P O'Connell; W Gorman; N O'Brien; C O'Herlihy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  63     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1988-11-18     Completed Date:  1988-11-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1065-8     Citation Subset:  AIM; IM    
Rotunda Hospital, Dublin.
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MeSH Terms
Asphyxia Neonatorum / complications*
Birth Weight
Delivery, Obstetric
Epilepsy / etiology*
Feeding Behavior
Infant, Newborn
Labor, Induced
Pregnancy, Prolonged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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