| Neonatal posterior cerebral artery stroke: clinical presentation, MRI findings, and outcome. | |
| | |
MedLine Citation:
|
PMID: 23336217 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
AIM: To report the clinical presentation, magnetic resonance imaging (MRI) findings, and follow-up data of newborn infants with perinatal arterial ischemic stroke in the territory of the posterior cerebral artery (PCA). METHOD: Data on 18 newborn infants from three neonatal intensive care units (11 males, seven females) with an MRI-confirmed PCA stroke were analysed and reported. Infants were born at a mean gestational age of 38.7 weeks (SD 3.4) with a mean birthweight of 3244g (SD 850). RESULTS: Fourteen infants presented with clinical seizures. Five of these had associated hypoxic-ischemic encephalopathy, four had hypoglycaemia, and five had neither hypoxic-ischemic encephalopathy nor hypoglycaemia. Subclinical seizures were present in one infant with hypoxic-ischemic encephalopathy and one with meningitis. One preterm infant presented with apnoeas and one had hypoxic-ischemic encephalopathy without seizures. Neurodevelopmental follow-up of 17 children at a median age of 36 months (SD 28, range 12-120mo) showed five with a global delay. Two children with additional injury developed postneonatal epilepsy and one child with extensive injury developed hemiplegia. A visual field defect was observed in nine children (six hemianopia, three quadrantanopia). In the 11 children with a second MRI at 3 months, the asymmetry of the optic radiation correlated with the development of a visual field deficit. INTERPRETATION: Outcome after PCA stroke is fairly good, depending on additional brain injury. Follow-up is required, as subsequent visual field defects are frequently observed. Further research will be needed to clarify the role of hypoglycaemia in perinatal arterial ischemic stroke. |
| | |
Authors:
|
Niek E van der Aa; Jeroen Dudink; Manon J N L Benders; Paul Govaert; Henrica L M van Straaten; Giorgio L Porro; Floris Groenendaal; Linda S de Vries |
Related Documents
:
|
2807667 - Societies in transition: mortality patterns in pacific island populations. 14760027 - Cdc's national violent death reporting system: background and methodology. 18380857 - Overview of deaths associated with natural events, united states, 1979-2004. 10410497 - Maternal mortality in ramathibodi hospital: a 28-year comparative study. 1444557 - Changes in the plasma aminogram of parenterally fed infants treated with dexamethasone ... 2051427 - Investigation and diagnosis of hypertrophic pyloric stenosis. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-22 |
Journal Detail:
|
Title: Developmental medicine and child neurology Volume: - ISSN: 1469-8749 ISO Abbreviation: Dev Med Child Neurol Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-22 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0006761 Medline TA: Dev Med Child Neurol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© The Authors. Developmental Medicine & Child Neurology © 2013 Mac Keith Press. |
Affiliation:
|
Department of Neonatology, Wilhelmina Children's Hospital, Utrecht, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Perovskite Sr1-xCexCoO3-? (0.05?x?0.15) as Superior Cathodes for Intermediate Temperature Solid Oxid...
Next Document: [Biological characteristics of bone marrow mesenchymal stem cells and JAK2 mutation in myeloprolifer...