Document Detail

Neonatal periventricular leukomalacia preceded by fetal periventricular echodensity.
MedLine Citation:
PMID:  10867479     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this prospective study is to verify whether fetal periventricular echodensity (PVE) precedes neonatal periventricular leukomalacia (PVL). METHODS: Fetal brains were studied with transvaginal scan in 63 high-risk fetuses from 17 to 32 weeks of pregnancy, PVE echogenicity was quantified with ultrasonic histogram, and neonatal brains and clinical courses were studied after birth. RESULTS: No fetal cystic PVL was found, instead, fetal PVE was detected in 42 fetuses. The quantified echogenicity value was higher in PVE than in normal brain. Four cases developed neonatal PVL among 28 preterm and 1 among 14 term births. Neonatal PVL developed in the 23 cases of persistent fetal PVE, whereas no neonatal PVL was found when fetal PVE was negative or disappeared. Cord compression signs were common in PVL cases. CONCLUSION: Neonatal PVL was preceded by antepartum persistent fetal PVE in the present study.
N Yamamoto; M Utsu; M Serizawa; S Ohki; T Murakoshi; M Seguchi; K Iwase; K Maeda
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  15     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:    2000 Jul-Aug
Date Detail:
Created Date:  2000-08-23     Completed Date:  2000-08-23     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  198-208     Citation Subset:  IM    
Copyright Information:
Copyright 2000 S. Karger AG, Basel.
Department of Obstetrics and Gynecology, Seirei Mikatahara Hospital, Hamamatsu, Japan.
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MeSH Terms
Cerebral Palsy / etiology
Cerebral Ventricles / embryology*,  ultrasonography*
Diseases in Twins
Gestational Age
Infant, Newborn
Infant, Premature
Leukomalacia, Periventricular / complications,  ultrasonography*
Obstetric Labor, Premature
Risk Factors

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