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Neonatal outcomes in pregnancies after bariatric surgery: A retrospective multicentric cohort study in three French referral centers.
MedLine Citation:
PMID:  23043220     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective: To analyze short-term neonatal outcomes in pregnancies after bariatric surgery according to procedure, to the body mass index (BMI) at the beginning of the pregnancy and to the interval from surgery to conception, using a retrospective multicentric cohort study in three French tertiary perinatal care and bariatric centers. Methods: 94 neonates in 79 women were included. Frequencies of adverse neonatal events by procedure, laparoscopic adjustable gastric banding (LAGB, n=63) or Roux-en-Y gastric bypass (RYGB, n=31), BMI class (72 women with BMI≥30 kg/m(2)) and interval between surgery and conception (43 deliveries of patients who conceived during the first postoperative year) were compared with chi-square tests. For parametric continuous data, t-tests or analysis of variance were used; nonparametric distributions were compared with the Wilcoxon or Kruskal-Wallis tests. Results: Significantly lower mean birth weight (2993g vs. 3253g; P=0.02) was observed after RYGB and the mean Z-score for birth weight was significantly closer to 0 in neonates of the LAGB group than in those of the RYGB group. However, no significant differences were noticed regarding small-for-gestational age (32.3% vs. 17.1%; P=0.06), umbilical arterial blood pH<7.0 (9.7% vs. 0%; P=0.11), low Apgar scores, perinatal mortality, and NICU admission. Neonatal outcomes according to the interval from surgery to conception or to the BMI at the beginning of the pregnancy were not significantly different. Conclusions: The short-term neonatal outcomes are basically comparable in pregnancies after RYGB than after LAGB.
Authors:
Guillaume Ducarme; Laura Parisio; Pietro Santulli; Lionel Carbillon; Laurent Mandelbrot; Dominique Luton
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-9
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Obstetrics and Gynecology, Assistance Publique-Hôpitaux de Paris (AP-HP), Beaujon hospital, Université Paris 7, 92110 Clichy, France.
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