Document Detail

Neonatal outcome of infants born at 500 to 800 grams from 1990 through 1998 in a tertiary care center.
MedLine Citation:
PMID:  12368972     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess if there have been changes in survival, demographic data, obstetric features, neonatal morbidity, and short-term neurologic/radiographic/neurosensory outcome of 500- to 800-g infants born in a tertiary care neonatal center from 1990 through 1998. STUDY DESIGN: Records of all 500- to 800-g infants born at North Shore University Hospital during 1990-1998 were reviewed to determine demographic data, survival by weight and gestational age (GA), obstetric features, neonatal morbidity, and short-term neurologic/radiographic/neurosensory outcome. Newborn infants were grouped into three triennia: 1990-1992, 1993-1995, and 1996-1998 and compared across time. RESULTS: Of the 173 infants admitted to the neonatal intensive care unit, 112 survived. Improved survival was documented: 40% in 1990-1992, 73% in 1993-1995, and 81% in 1996-1998 (p < 0.0001). Improved survival was also noted in each of the three weight cohorts, as well as in infants < or =26 weeks GA. An increased use of antenatal corticosteroids and increased number of deliveries by cesarean section (C/S) were noted across time. The incidence of 0 to 3 Apgar scores at both 1 and 5 minutes decreased across time. Necrotizing enterocolitis in survivors and expected short-term neurologic/radiographic/neurosensory outcome improved between 1990-1992 and 1996-1998, with a trend toward reduced IVH grade III to IV. The incidence of other neonatal morbidities did not change throughout the time period. CONCLUSIONS: The data document that survival rates continued to improve for 500- to 800-g infants throughout the 1990s. This was concurrent with an increase in "low-risk, expected normal" infants, increased number of deliveries by C/S, decreased incidence of low Apgar scores at both 1 and 5 minutes, and an increased use of antenatal corticosteroids.
Rita G Harper; Khalil U Rehman; Concepcion Sia; Sharon Buckwald; Regina Spinazzola; Jerrold Schlessel; Judith Mestrandrea; Mary Rodgers; Raul A Wapnir
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  22     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:    2002 Oct-Nov
Date Detail:
Created Date:  2002-10-07     Completed Date:  2002-12-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  555-62     Citation Subset:  IM    
Department of Pediatrics, Division of Neonatal/Perinatal Medicine, Schneider Children's Hospital at North Shore, North Shore-Long Island Jewish Health System, Manhasset, NY, USA.
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MeSH Terms
Apgar Score
Gestational Age
Infant Mortality*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / epidemiology*
Infant, Very Low Birth Weight*
New York / epidemiology
Retrospective Studies

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