| Neonatal outcome of infants born at 500 to 800 grams from 1990 through 1998 in a tertiary care center. | |
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MedLine Citation:
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PMID: 12368972 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess if there have been changes in survival, demographic data, obstetric features, neonatal morbidity, and short-term neurologic/radiographic/neurosensory outcome of 500- to 800-g infants born in a tertiary care neonatal center from 1990 through 1998. STUDY DESIGN: Records of all 500- to 800-g infants born at North Shore University Hospital during 1990-1998 were reviewed to determine demographic data, survival by weight and gestational age (GA), obstetric features, neonatal morbidity, and short-term neurologic/radiographic/neurosensory outcome. Newborn infants were grouped into three triennia: 1990-1992, 1993-1995, and 1996-1998 and compared across time. RESULTS: Of the 173 infants admitted to the neonatal intensive care unit, 112 survived. Improved survival was documented: 40% in 1990-1992, 73% in 1993-1995, and 81% in 1996-1998 (p < 0.0001). Improved survival was also noted in each of the three weight cohorts, as well as in infants < or =26 weeks GA. An increased use of antenatal corticosteroids and increased number of deliveries by cesarean section (C/S) were noted across time. The incidence of 0 to 3 Apgar scores at both 1 and 5 minutes decreased across time. Necrotizing enterocolitis in survivors and expected short-term neurologic/radiographic/neurosensory outcome improved between 1990-1992 and 1996-1998, with a trend toward reduced IVH grade III to IV. The incidence of other neonatal morbidities did not change throughout the time period. CONCLUSIONS: The data document that survival rates continued to improve for 500- to 800-g infants throughout the 1990s. This was concurrent with an increase in "low-risk, expected normal" infants, increased number of deliveries by C/S, decreased incidence of low Apgar scores at both 1 and 5 minutes, and an increased use of antenatal corticosteroids. |
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Authors:
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Rita G Harper; Khalil U Rehman; Concepcion Sia; Sharon Buckwald; Regina Spinazzola; Jerrold Schlessel; Judith Mestrandrea; Mary Rodgers; Raul A Wapnir |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 22 ISSN: 0743-8346 ISO Abbreviation: J Perinatol Publication Date: 2002 Oct-Nov |
Date Detail:
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Created Date: 2002-10-07 Completed Date: 2002-12-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 555-62 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Division of Neonatal/Perinatal Medicine, Schneider Children's Hospital at North Shore, North Shore-Long Island Jewish Health System, Manhasset, NY, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Apgar Score Female Gestational Age Humans Infant Mortality* Infant, Newborn Infant, Premature Infant, Premature, Diseases / epidemiology* Infant, Very Low Birth Weight* Male New York / epidemiology Retrospective Studies |
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