Document Detail

Neonatal neutropenia in low birthweight premature infants.
MedLine Citation:
PMID:  7710574     Owner:  NLM     Status:  MEDLINE    
Neutropenia, as defined by common reference values, occurs often in neonates. Its incidence, causes, and clinical consequences have not been studied extensively in premature neonates. Of 208 consecutive infants with birthweight up to 2000 g, 121 (58%) had neutropenia. Low gestational age and low birthweight correlated with the incidence of neutropenia. Less than half of the neutropenic episodes could be attributed to infections, the others were related to specific perinatal events and due to drug therapy or were of unknown cause. Neutropenia following treatment with certain antibiotics was the most common cause of neutropenia occurring after the second week of life. The high incidence of neutropenia in premature neonates raises questions about application of these reference ranges to low birthweight infants and suggests the need for new reference values.
P Gessler; R Lüders; S König; N Haas; P Lasch; W Kachel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  12     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1995-05-18     Completed Date:  1995-05-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  34-8     Citation Subset:  IM    
Department of Pediatrics, University Hospital of Mannheim, Germany.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Bacterial Infections / blood,  drug therapy
Infant, Low Birth Weight / blood
Infant, Newborn
Infant, Premature / blood
Infant, Premature, Diseases / blood,  epidemiology*
Neutropenia / epidemiology*,  etiology
Reference Values
Retrospective Studies
Risk Factors
Reg. No./Substance:
0/Anti-Bacterial Agents
Comment In:
Am J Perinatol. 1995 Sep;12(5):375-6   [PMID:  8540948 ]

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