Document Detail

Neonatal neurodevelopmental examination as a predictor of neuromotor outcome in premature infants.
MedLine Citation:
PMID:  2927988     Owner:  NLM     Status:  MEDLINE    
There was a marked correlation (P less than .000001) between neonatal neurodevelopmental examination results and neuromotor outcome at 1 year of age or older in 210 high-risk premature infants (mean birth weight 1,107 g, mean gestational age 28.4 weeks). This neonatal examination consisted of assessment of posture, extremity and axial tone, deep tendon reflexes, pathologic reflexes, primitive reflexes, symmetry, oromotor function, cranial nerve function, auditory and visual responses, and behavior. Premature infants whose neonatal neurodevelopmental examination results were abnormal had significantly higher incidences of both cerebral palsy (38% v 6%, P less than .000001) and minor neuromotor dysfunction (27% v 13%, p less than .05) than did premature infants whose examination results were normal. This correlation continued to be highly significant even with the analysis of subgroups (infants born at or before 27 weeks' gestation, infants with chronic lung disease discharged with oxygen supplementation, infants with periventricular hemorrhage) and when a variety of individual perinatal, demographic, and social variables were used as controls. Normal or nearly normal neonatal neurodevelopmental examination results can be used to reassure parents of high-risk premature infants. Although abnormal neonatal neurodevelopmental examination results cannot be used to diagnose handicap in premature infants, they can be used to select a group of high-risk infants who should be carefully monitored during infancy and childhood.
M C Allen; A J Capute
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics     Volume:  83     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1989 Apr 
Date Detail:
Created Date:  1989-04-28     Completed Date:  1989-04-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  498-506     Citation Subset:  AIM; IM    
Johns Hopkins Hospital, Baltimore, MD 21205.
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MeSH Terms
Cerebral Palsy / diagnosis*
Child Development
Infant, Newborn
Infant, Premature, Diseases / physiopathology*
Nervous System / growth & development
Nervous System Diseases / diagnosis*
Neurologic Examination*
Predictive Value of Tests
Psychomotor Performance*
Socioeconomic Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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