Document Detail

Neonatal lupus erythematosus in four successive siblings born to a mother with discoid lupus erythematosus.
MedLine Citation:
PMID:  6334534     Owner:  NLM     Status:  MEDLINE    
A young woman with inactive discoid lupus erythematosus (LE) gave birth in three successive pregnancies to four male infants who showed cutaneous, and in one case cardiac, signs of neonatal LE. The mother had Ro and La antibodies although the anti-nuclear factor (ANF) was not consistently detectable. Three of the infants received phototherapy for neonatal jaundice. Maternal discoid LE may give rise to neonatal LE, and successive siblings can be affected.
D J Gawkrodger; G W Beveridge
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  111     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-02-08     Completed Date:  1985-02-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  683-7     Citation Subset:  IM    
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MeSH Terms
Antibodies, Antinuclear / analysis
Heart Block / congenital,  etiology
Infant, Newborn
Lupus Erythematosus, Discoid / congenital*,  genetics,  immunology
Maternal-Fetal Exchange
Pregnancy Complications / immunology
Reg. No./Substance:
0/Antibodies, Antinuclear

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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