Document Detail

Neonatal lupus erythematosus: five new cases with HLA typing.
MedLine Citation:
PMID:  6602647     Owner:  NLM     Status:  MEDLINE    
In two of five infants with neonatal lupus erythematosus the signs of the disease did not appear until the children had been exposed to direct sunlight. This suggests that an environmental factor may be required for the development of the disease in some patients. Three of the five patients, together with their mothers, had the HLA (histocompatibility) antigens A1 and B8, which supports the concept that individuals may be genetically susceptible to lupus erythematosus.
K A Barber; R Jackson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  129     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1983 Jul 
Date Detail:
Created Date:  1983-08-11     Completed Date:  1983-08-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  139-41     Citation Subset:  AIM; IM    
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MeSH Terms
HLA Antigens / genetics*
HLA-A1 Antigen
HLA-B8 Antigen
Infant, Newborn
Infant, Newborn, Diseases / genetics*
Lupus Erythematosus, Systemic / genetics*
Reg. No./Substance:
0/HLA Antigens; 0/HLA-A1 Antigen; 0/HLA-B8 Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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