Document Detail


Neonatal leukemoid reaction associated with Candida albicans chorioamnionitis.
MedLine Citation:
PMID:  24730633     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Chorioamnionitis due to Candida species is relatively rare, despite the high prevalence (20-25%) of Candida vulvovaginitis during pregnancy. We describe a case of neonatal leukemoid reaction (NLR) associated with Candida albicans chorioamnionitis. A male infant was born at 31 weeks' gestation and weighed 1864 g. Laboratory tests at birth indicated marked leukocytosis (i.e. total leukocyte count 89.8 × 10(9) /L including 66% polymorphonuclear leukocytes and 15% band forms). Samples of the infant's pharyngeal mucus and tracheal aspirate were positive for Candida albicans. On further histopathology of the placenta, C. albicans mycelia had invaded the placenta, chorioamniotic membrane, and umbilical cord. Although it is not very common, C. albicans chorioamnionitis should be considered in preterm infants with NLR.
Authors:
Sota Iwatani; Masami Mizobuchi; Toshiki Sofue; Satoshi Tanaka; Hitomi Sakai; Seiji Yoshimoto; Hideto Nakao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics international : official journal of the Japan Pediatric Society     Volume:  56     ISSN:  1442-200X     ISO Abbreviation:  Pediatr Int     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-04-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886002     Medline TA:  Pediatr Int     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  277-9     Citation Subset:  IM    
Copyright Information:
© 2014 The Authors. Pediatrics International © 2014 Japan Pediatric Society.
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