Document Detail

Neonatal and infant feeding: effect on bone density at 4 years.
MedLine Citation:
PMID:  15990636     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of this study was to determine whether the type of feeding during the first 4 months of life affects bone mineral density at 4 years of age. METHODS: Healthy 4-year-old children were recruited from the offices of primary health care providers. After confirming the type of infant feeding by history, dual energy x-ray absorptiometry analysis was obtained at the University of Nebraska Medical Center and evaluated by a radiologist blinded as to feeding type. RESULTS: One hundred and seventy-eight children completed the study (58% male, 85% Caucasian; mean age, 4.5 years). All children had exclusively consumed human milk (n = 57), an infant formula containing no palm olein oil (n = 56) or an infant formula containing palm olein oil (n = 65) during the first 4 months of life. At 4 years of age, no significant differences were noted in bone mineral content or bone mineral density (P = 0.51 and 0.89, respectively) among the three feeding groups as measured by dual energy x-ray absorptiometry. Total body bone mineral content and bone mineral density varied by gender, with males having significantly higher values than females regardless of feeding type (P = 0.028 and P < 0.001, respectively). CONCLUSION: There is no association between the use of palm olein formula during the first 4 months of life and subsequent bone mineral content and bone mineral density in healthy 4-year-old children.
Rosemary J Young; Dean L Antonson; Paul W Ferguson; Nancy D Murray; Kim Merkel; Timothy E Moore
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric gastroenterology and nutrition     Volume:  41     ISSN:  0277-2116     ISO Abbreviation:  J. Pediatr. Gastroenterol. Nutr.     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-07-01     Completed Date:  2005-11-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8211545     Medline TA:  J Pediatr Gastroenterol Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  88-93     Citation Subset:  IM    
University of Nebraska Medical Center, Omaha, Nebraska 68198-5160, USA.
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MeSH Terms
Absorptiometry, Photon / methods
Body Composition
Bone Density / drug effects,  physiology*
Bone Development / drug effects,  physiology
Child, Preschool
Infant Food*
Infant Formula / chemistry
Infant Nutritional Physiological Phenomena*
Infant, Newborn
Lumbar Vertebrae / radiography
Milk, Human / chemistry
Minerals / administration & dosage,  pharmacology
Nutritive Value
Plant Oils / administration & dosage,  pharmacology
Sex Characteristics
Spine / radiography
Reg. No./Substance:
0/Minerals; 0/Plant Oils; 8002-75-3/palm oil

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