| Neonatal goiter caused by expectorant usage. | |
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MedLine Citation:
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PMID: 11592576 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A female newborn was admitted with the symptoms of mild respiratory distress, protruding tongue, hypotonicity, cutis marmorata, sclerema, myxedema, abdominal distension, and feeding problems on the first day of life. She had a huge neck mass, a large anterior and posterior fontanel, and hoarse cry. She had no umbilical hernia or jaundice. A history of maternal potassium iodine (expectorant) usage without doctor's advice was obtained; the mother had not attended a clinic throughout the pregnancy. On ultrasonographic examination, the thyroid right lobe was 53 x 31 mm and the left lobe was 34 x 31 mm. The results of thyroid hormone tests on the first day were as follows: T3 20 ng/dl (normal: 32-216 ng/dl), T4 0.9 microg/dl (11.8-22.6 microg/dl), TSH 120 mIU/l (2.5-13.3 mIU/l). This patient is presented to emphasize the role of hypothyroidism in drug-induced neonatal goiter and to discuss the possibility of a life-threatening effect of congenital goiter, i.e. respiratory tract obstruction. |
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Authors:
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I Bostanci; A Sarioģlu; H Ergin; A Akşit; M Cinbiş; N Akalin |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric endocrinology & metabolism : JPEM Volume: 14 ISSN: 0334-018X ISO Abbreviation: J. Pediatr. Endocrinol. Metab. Publication Date: 2001 Sep-Oct |
Date Detail:
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Created Date: 2001-10-10 Completed Date: 2002-02-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9508900 Medline TA: J Pediatr Endocrinol Metab Country: England |
Other Details:
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Languages: eng Pagination: 1161-2 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Pamukkale University, Denizli, Turkey. ebb@e-kolay.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Expectorants
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adverse effects* Female Goiter / chemically induced*, ultrasonography Humans Infant, Newborn Maternal-Fetal Exchange* Potassium Iodide / adverse effects* Pregnancy Thyroid Gland / ultrasonography Thyroxine / blood Triiodothyronine / blood |
| Chemical | |
Reg. No./Substance:
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0/Expectorants; 6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine; 7681-11-0/Potassium Iodide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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