Document Detail

Neonatal goiter caused by expectorant usage.
MedLine Citation:
PMID:  11592576     Owner:  NLM     Status:  MEDLINE    
A female newborn was admitted with the symptoms of mild respiratory distress, protruding tongue, hypotonicity, cutis marmorata, sclerema, myxedema, abdominal distension, and feeding problems on the first day of life. She had a huge neck mass, a large anterior and posterior fontanel, and hoarse cry. She had no umbilical hernia or jaundice. A history of maternal potassium iodine (expectorant) usage without doctor's advice was obtained; the mother had not attended a clinic throughout the pregnancy. On ultrasonographic examination, the thyroid right lobe was 53 x 31 mm and the left lobe was 34 x 31 mm. The results of thyroid hormone tests on the first day were as follows: T3 20 ng/dl (normal: 32-216 ng/dl), T4 0.9 microg/dl (11.8-22.6 microg/dl), TSH 120 mIU/l (2.5-13.3 mIU/l). This patient is presented to emphasize the role of hypothyroidism in drug-induced neonatal goiter and to discuss the possibility of a life-threatening effect of congenital goiter, i.e. respiratory tract obstruction.
I Bostanci; A Sarioģlu; H Ergin; A Akşit; M Cinbiş; N Akalin
Related Documents :
9800676 - Delaying surgery for thyroid cancer in pregnancy. a case report.
22654966 - Bladder cancer in the second trimester of pregnancy: tough decisions. a case report wit...
8855626 - A study of 111 cases of globus hystericus.
23229416 - Effects of paternal folate deficiency on the expression of insulin-like growth factor-2...
12962946 - A comparison of isosorbide mononitrate and misoprostol cervical ripening before suction...
16405406 - Intrauterine diagnosis and management of fetal goitrous hypothyroidism: a report of an ...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  14     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:    2001 Sep-Oct
Date Detail:
Created Date:  2001-10-10     Completed Date:  2002-02-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  1161-2     Citation Subset:  IM    
Department of Pediatrics, Pamukkale University, Denizli, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Expectorants / adverse effects*
Goiter / chemically induced*,  ultrasonography
Infant, Newborn
Maternal-Fetal Exchange*
Potassium Iodide / adverse effects*
Thyroid Gland / ultrasonography
Thyroxine / blood
Triiodothyronine / blood
Reg. No./Substance:
0/Expectorants; 6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine; 7681-11-0/Potassium Iodide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Gliclazide-induced hepatitis, hemiplegia and dysphasia in a suicide attempt.
Next Document:  Idiopathic hypothalamic dysfunction with precocious puberty and adipsic hypernatremia first presenti...