| Neonatal fat digestion and lingual lipase. | |
| | |
MedLine Citation:
|
PMID: 3105239 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Lingual lipase (LL) activity, pH, and products of fat hydrolysis were determined in gastric aspirates from preterm infants who received formula milk feeds by a nasogastric tube. In 1-hourly (n = 9), 2-hourly (n = 8) and 3-hourly (n = 9) fed infants LL activity increased to reach its maximum value at 60, 90, and 120 min respectively after the feeds, and gastric pH levels fell from about 6.0 to less than 3.5. There was a reduction in triglyceride content to 50% of the initial value, measured immediately after a feed, and the products of hydrolysis were mainly diglycerides and FFA. In a subsequent study 3-hourly fed infants (n = 8) had a tube feed followed by a bottle feed, and then a bottle feed followed by a tube feed on successive days (cross-over). The LL activity observed after a bottle feed (mean maximal value 23.8 mumol FFA/ml/h) was significantly higher than after a tube feed (19.1 mumol FFA/ml/h). It is suggested that substantial triglyceride hydrolysis takes place in the stomach due to lingual lipase, and sucking seems to enhance enzyme production. |
| | |
Authors:
|
L J Smith; S Kaminsky; S W D'Souza |
Related Documents
:
|
18768269 - Nutritive sucking pattern--from very low birth weight preterm to term newborn. 2702299 - Decision rules for infant feeding: the influence of maternal expertise, regulating func... 18576529 - Kinetics of ethanol production during the reactor feeding phase in constant feb-batch f... 15739719 - Effect of an oral stimulation program on sucking skill maturation of preterm infants. 1733819 - Oral-motor dysfunction and feeding disorders of infants with turner syndrome. 10433159 - Efficacy of gastrostomy feeding in infants and older children receiving chronic periton... 6112419 - Outcome for infants of very low birthweight: survey of world literature. 22674669 - Same but different: 9-month-old infants at average and high risk for autism look at the... 11324189 - Infant botulism: case reports and review. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Acta paediatrica Scandinavica Volume: 75 ISSN: 0001-656X ISO Abbreviation: Acta Paediatr Scand Publication Date: 1986 Nov |
Date Detail:
|
Created Date: 1987-05-21 Completed Date: 1987-05-21 Revised Date: 2009-11-11 |
Medline Journal Info:
|
Nlm Unique ID: 0000211 Medline TA: Acta Paediatr Scand Country: SWEDEN |
Other Details:
|
Languages: eng Pagination: 913-8 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Dietary Fats
/
metabolism* Enteral Nutrition Fatty Acids, Nonesterified / metabolism Gastric Juice / analysis Humans Hydrogen-Ion Concentration Hydrolysis Infant Infant Food Infant, Newborn Infant, Premature / growth & development, metabolism* Lipase / metabolism* Tongue / enzymology* Triglycerides / metabolism |
| Chemical | |
Reg. No./Substance:
|
0/Dietary Fats; 0/Fatty Acids, Nonesterified; 0/Triglycerides; EC 3.1.1.3/Lipase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Does centralized treatment of cystic fibrosis increase the risk of Pseudomonas aeruginosa infection?
Next Document: Plasma growth hormone (GH) responses to growth hormone releasing factor (hp GRF 1-44) in familial GH...