| Neonatal extra-corporeal life support: indications and limitations. | |
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MedLine Citation:
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PMID: 18346856 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiac extra-corporeal life support is used more frequently in the current era of complex, high-risk neonatal heart surgery. Although outcome for neonates with complex heart disease has improved in the last decade, thanks to advances in surgery and intensive care, survival in the subset that require extra-corporeal support remains unchanged at below 40%. Neonatal cardiac extra-corporeal support is a technically challenging therapy that is applied in a range of contexts including: post-operative low cardiac output syndrome, cardiac arrest, high-risk interventional catheterisation or as a bridge to recovery from dysrhythmia and myocarditis. Extra-corporeal life support has increased in particular for neonates with single ventricle disease in the last 5 years, mainly achieving similar results to biventricular patients. Further research is required in order to determine the optimal methods for patient selection and to establish important predictors of outcome including the longterm neurological development of survivors. |
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Authors:
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Kate L Brown; Allan P Goldman |
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Publication Detail:
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Type: Journal Article; Practice Guideline; Review Date: 2008-03-17 |
Journal Detail:
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Title: Early human development Volume: 84 ISSN: 0378-3782 ISO Abbreviation: Early Hum. Dev. Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-03-31 Completed Date: 2008-06-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7708381 Medline TA: Early Hum Dev Country: Ireland |
Other Details:
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Languages: eng Pagination: 143-8 Citation Subset: IM |
Affiliation:
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Cardiac Intensive Care Unit, Great Ormond Street Hospital for Sick Children, Great Ormond Street, London WC1N 3JH, UK. brownk@gosh.nhs.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Extracorporeal Membrane Oxygenation
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methods* Heart Defects, Congenital / diagnosis, surgery, therapy* Heart-Assist Devices* Humans Infant, Newborn |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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