| Neonatal encephalopathy: an inadequate term for hypoxic-ischemic encephalopathy. | |
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MedLine Citation:
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PMID: 22926849 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This Point of View article addresses neonatal encephalopathy (NE) presumably caused by hypoxia-ischemia and the terminology currently in wide use for this disorder. The nonspecific term NE is commonly utilized for those infants with the clinical and imaging characteristics of neonatal hypoxic-ischemic encephalopathy (HIE). Multiple magnetic resonance imaging studies of term infants with the clinical setting of presumed hypoxia-ischemia near the time of delivery have delineated a topography of lesions highly correlated with that defined by human neuropathology and by animal models, including primate models, of hypoxia-ischemia. These imaging findings, coupled with clinical features consistent with perinatal hypoxic-ischemic insult(s), warrant the specific designation of neonatal HIE. |
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Authors:
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Joseph J Volpe |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of neurology Volume: 72 ISSN: 1531-8249 ISO Abbreviation: Ann. Neurol. Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-08-28 Completed Date: 2012-11-01 Revised Date: 2013-02-11 |
Medline Journal Info:
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Nlm Unique ID: 7707449 Medline TA: Ann Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 156-66 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 American Neurological Association. |
Affiliation:
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Department of Neurology, Harvard Medical School, Children's Hospital Boston, Boston, MA 02115, USA. Joseph.volpe@childrens.harvard.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Diagnostic Imaging Disease Models, Animal Female Humans Hypoxia-Ischemia, Brain* / diagnosis, physiopathology, therapy Infant Infant, Newborn Infant, Newborn, Diseases* / diagnosis, physiopathology, therapy Magnetic Resonance Imaging Male Pregnancy Pregnancy Complications / physiopathology |
| Comments/Corrections | |
Comment In:
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Ann Neurol. 2012 Dec;72(6):984-5
[PMID:
23280849
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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