| Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. | |
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MedLine Citation:
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PMID: 987769 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-one neonates of over 36 weeks' gestation suffered perinatal asphyxia but not chronic hypoxia. Three clinical stages of postanoxic encephalopathy were distinguished. Stage 1 lasted less than 24 hours and was characterized by hyperalertness, uninhibited Moro and stretch reflexes, sympathetic effects, and a normal electroencephalogram. Stage 2 was marked by obtundation, hypotonia, strong distal flexion, and multifocal seizures. The EEG showed a periodic pattern sometimes preceded by continuous delta activity. Infants in stage 3 were stuporous, flaccid, and brain stem and autonomic functions were suppressed. The EEG was isopotential or had infrequent periodic discharges. Infants who did not enter stage 3 and who had signs of stage 2 for less than five days appeared normal in later infancy. Persistence of stage 2 for more than seven days or failure of the EEG to revert to normal was associated with later neurologic impairment or death. |
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Authors:
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H B Sarnat; M S Sarnat |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of neurology Volume: 33 ISSN: 0003-9942 ISO Abbreviation: Arch. Neurol. Publication Date: 1976 Oct |
Date Detail:
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Created Date: 1976-12-03 Completed Date: 1976-12-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 696-705 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Brain Diseases
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etiology*,
physiopathology Consciousness Female Fetal Distress / complications* Humans Infant Infant, Newborn Infant, Newborn, Diseases / etiology*, physiopathology Myoclonus / physiopathology Parasympathetic Nervous System / physiopathology Posture Pregnancy Prognosis Seizures / physiopathology Sleep Sympathetic Nervous System / physiopathology Time Factors Wakefulness |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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