|Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study.|
|PMID: 987769 Owner: NLM Status: MEDLINE|
|Twenty-one neonates of over 36 weeks' gestation suffered perinatal asphyxia but not chronic hypoxia. Three clinical stages of postanoxic encephalopathy were distinguished. Stage 1 lasted less than 24 hours and was characterized by hyperalertness, uninhibited Moro and stretch reflexes, sympathetic effects, and a normal electroencephalogram. Stage 2 was marked by obtundation, hypotonia, strong distal flexion, and multifocal seizures. The EEG showed a periodic pattern sometimes preceded by continuous delta activity. Infants in stage 3 were stuporous, flaccid, and brain stem and autonomic functions were suppressed. The EEG was isopotential or had infrequent periodic discharges. Infants who did not enter stage 3 and who had signs of stage 2 for less than five days appeared normal in later infancy. Persistence of stage 2 for more than seven days or failure of the EEG to revert to normal was associated with later neurologic impairment or death.|
|H B Sarnat; M S Sarnat|
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|Type: Journal Article|
|Title: Archives of neurology Volume: 33 ISSN: 0003-9942 ISO Abbreviation: Arch. Neurol. Publication Date: 1976 Oct|
|Created Date: 1976-12-03 Completed Date: 1976-12-03 Revised Date: 2004-11-17|
Medline Journal Info:
|Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: UNITED STATES|
|Languages: eng Pagination: 696-705 Citation Subset: AIM; IM|
|APA/MLA Format Download EndNote Download BibTex|
Fetal Distress / complications*
Infant, Newborn, Diseases / etiology*, physiopathology
Myoclonus / physiopathology
Parasympathetic Nervous System / physiopathology
Seizures / physiopathology
Sympathetic Nervous System / physiopathology
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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