| Neonatal complications of preterm premature rupture of membranes. Pathophysiology and management. | |
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MedLine Citation:
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PMID: 11817188 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Midtrimester PROM is an infrequent, yet potentially disastrous complication of pregnancy. The most likely neonatal complication is preterm delivery with associated morbidity and mortality risks. Unique neonatal complications following PPROM include skeletal deformations and pulmonary hypoplasia related to prolonged oligohydramnios exposure. A systematic approach to an infant with respiratory insufficiency following PPROM delivery is possible with an understanding of the pathophysiology of pulmonary hypoplasia. Neonatal management should include immediate resuscitation including surfactant replacement, with careful attention to techniques of mechanical ventilation to avoid early volutrauma. Adjunctive therapies directed at pulmonary hypertension may now permit survival of some infants with less severe forms of pulmonary hypoplasia. |
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Authors:
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H W Kilbride; D W Thibeault |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Clinics in perinatology Volume: 28 ISSN: 0095-5108 ISO Abbreviation: Clin Perinatol Publication Date: 2001 Dec |
Date Detail:
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Created Date: 2001-12-05 Completed Date: 2002-05-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7501306 Medline TA: Clin Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 761-85 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Section of Neonatal Medicine, Children's Mercy Hospitals and Clinics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA. hkilbride@cmh.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Fetal Membranes, Premature Rupture / complications*, physiopathology* Humans Infant Care Infant, Newborn Infant, Newborn, Diseases / diagnosis, etiology*, physiopathology*, therapy Infant, Premature Pregnancy Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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