| Neonatal changes in fatty acid profile of phospholipids in rat heart muscle. | |
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MedLine Citation:
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PMID: 6860703 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The fatty acid composition of rat heart phospholipids was examined during the neonatal and postnatal period. The rats were killed on days 1, 7, 14 and 21 after birth and at the ages of 2 and 6 months. The fatty acyl chain composition of the two major phospholipids, phosphatidylcholine (PC) and phosphatidylethanolamine (PE) changed significantly during the first 2 months. In PC there was a marked and immediate increase in stearic acid, a significant but transient increase in arachidonic acid and late increase in linoleic acid content. In PE there was an immediate increase in stearic acid and docosahexaenoic acid, followed by a late increase in linoleic acid content. The observed alterations in fatty acid composition of heart muscle phospholipids resemble changes induced by repeated administration of norepinephrine and subsequent recovery. Neonatal stress and increased cardiac function play an important role in the modification of the fatty acid composition of rat heart muscle phospholipids during early development. |
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Authors:
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A Gudmundsdottir; S Gudbjarnason |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biochimica et biophysica acta Volume: 752 ISSN: 0006-3002 ISO Abbreviation: Biochim. Biophys. Acta Publication Date: 1983 Jul |
Date Detail:
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Created Date: 1983-08-26 Completed Date: 1983-08-26 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0217513 Medline TA: Biochim Biophys Acta Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 284-90 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aging Animals Animals, Newborn / metabolism* Chemical Phenomena Chemistry Fatty Acids / metabolism* Myocardium / metabolism* Phosphatidylcholines / metabolism* Phosphatidylethanolamines / metabolism* Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids; 0/Phosphatidylcholines; 0/Phosphatidylethanolamines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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