Document Detail

Neonatal bilirubin production after preterm labor tocolysis with nifedipine.
MedLine Citation:
PMID:  2721333     Owner:  NLM     Status:  MEDLINE    
We studied the in vivo total bilirubin production, as indexed by the carboxyhemoglobin level (HbCO), of infants whose mothers had ritodrine (RIT) tocolysis or underwent tocolysis with the calcium channel blocker, nifedipine (NIF). No difference in HbCO between the infant groups was detected: NIF 0.67 +/- 0.31% saturation and RIT 0.88 +/- 0.47% saturation. We conclude that NIF is unlikely to cause a clinically important increase in total bilirubin production when used at doses sufficient for tocolysis.
J E Ferguson; T E Schutz; D K Stevenson
Related Documents :
9056103 - Transcutaneous bilirubinometry: its role in the assessment of neonatal jaundice.
19948573 - Hereditary spherocytosis in neonates with hyperbilirubinemia.
7260783 - Neonatal screening in vancouver for congenital dislocation of the hip.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Developmental pharmacology and therapeutics     Volume:  12     ISSN:  0379-8305     ISO Abbreviation:  Dev Pharmacol Ther     Publication Date:  1989  
Date Detail:
Created Date:  1989-07-05     Completed Date:  1989-07-05     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8003947     Medline TA:  Dev Pharmacol Ther     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  113-7     Citation Subset:  IM    
Department of Gynecology and Obstetrics, Stanford University School of Medicine, Calif.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bilirubin / biosynthesis*
Blood Glucose / metabolism
Carboxyhemoglobin / metabolism
Gestational Age
Infant, Newborn
Nifedipine / adverse effects*
Obstetric Labor, Premature / prevention & control*
Tocolytic Agents / adverse effects*
Grant Support
Reg. No./Substance:
0/Blood Glucose; 0/Tocolytic Agents; 21829-25-4/Nifedipine; 635-65-4/Bilirubin; 9061-29-4/Carboxyhemoglobin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effect of chronic maternal drug addiction on placental drug metabolism.
Next Document:  Effects of acute administration of naltrexone on cardiovascular function, body temperature, body wei...