Document Detail

Neonatal alloimmune thrombocytopenia. A case report and a review of the literature.
MedLine Citation:
PMID:  8179559     Owner:  NLM     Status:  MEDLINE    
A 32-year-old woman in her third pregnancy underwent fetal blood sampling because of a previous child with neonatal thrombocytopenia. At 33 weeks' gestation, fetal thrombocytopenia was diagnosed. Treatment was instituted antenatally with serial fetal platelet transfusions and corticosteroid therapy. Delivery was by Caesarean section at 37 weeks' gestation. Neonatal treatment included further platelet transfusion and immunoglobulin infusion. Recovery of the neonate was complete on discharge from hospital 10 days after birth. The aetiology, diagnosis, clinical presentations and therapeutic options in cases of alloimmune thrombocytopenia are discussed.
A Lee; M Permezel; P Dennington; T Duke; L Doyle; H Robinson
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Australian & New Zealand journal of obstetrics & gynaecology     Volume:  33     ISSN:  0004-8666     ISO Abbreviation:  Aust N Z J Obstet Gynaecol     Publication Date:  1993 Nov 
Date Detail:
Created Date:  1994-06-07     Completed Date:  1994-06-07     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0001027     Medline TA:  Aust N Z J Obstet Gynaecol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  420-3     Citation Subset:  IM    
Royal Women's Hospital, University of Melbourne, Carlton.
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MeSH Terms
Antigens, Human Platelet / immunology
Betamethasone / administration & dosage
Blood Transfusion, Intrauterine
Fetal Diseases / diagnosis*,  immunology,  therapy
Gestational Age
Immunoglobulins, Intravenous / therapeutic use
Infant, Newborn
Platelet Transfusion
Prenatal Diagnosis*
Thrombocytopenia / diagnosis*,  immunology,  therapy
Reg. No./Substance:
0/Antigens, Human Platelet; 0/Immunoglobulins, Intravenous; 378-44-9/Betamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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