Document Detail

Neonatal acid-base status following general anesthesia for emergency abdominal delivery with halothane or isoflurane.
MedLine Citation:
PMID:  1562344     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: To determine whether halothane or isoflurane as anesthesia for emergency abdominal delivery is associated with better fetal acid-base parameters. DESIGN: Randomized study. SETTING: Inpatient Level III perinatal referral center in a university hospital. PATIENTS: Sixty-six gravidas undergoing emergency abdominal delivery under general anesthesia for fetal distress. INTERVENTIONS: Randomization to receive halothane or isoflurane at 0.7 minimum alveolar concentration as part of a standard anesthetic technique. MEASUREMENTS AND MAIN RESULTS: Umbilical artery and vein blood gases were obtained and compared for hydrogen ion concentration, partial pressure of carbon dioxide, partial pressure of oxygen, and base deficit. There were no significant differences between the isoflurane and halothane groups. CONCLUSIONS: There is no difference in the frequency or severity of acidosis associated with isoflurane or halothane when used for general anesthesia for emergency abdominal delivery of a distressed fetus.
B K Mokriski; A M Malinow
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of clinical anesthesia     Volume:  4     ISSN:  0952-8180     ISO Abbreviation:  J Clin Anesth     Publication Date:    1992 Mar-Apr
Date Detail:
Created Date:  1992-05-21     Completed Date:  1992-05-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8812166     Medline TA:  J Clin Anesth     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  97-100     Citation Subset:  IM    
Department of Anesthesiology, University of Maryland School of Medicine, Baltimore 21201.
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MeSH Terms
Acid-Base Equilibrium / physiology*
Anesthesia, Inhalation*
Anesthesia, Obstetrical*
Cesarean Section*
Fetal Distress
Infant, Newborn / physiology*
Reg. No./Substance:
151-67-7/Halothane; 26675-46-7/Isoflurane

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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