Document Detail

Neonatal Pain Control and Neurologic Effects of Anesthetics and Sedatives in Preterm Infants.
MedLine Citation:
PMID:  24524456     Owner:  NLM     Status:  Publisher    
Preclinical and clinical studies have demonstrated the adverse consequences of untreated pain and stress on brain development in the preterm infant. Sucrose has widely been implemented as standard therapy for minor procedural pain. Anesthetics are commonly utilized in preterm infants during major surgery. Pharmacologic agents (benzodiazepines and opioids) have been examined in clinical trials of preterm infants requiring invasive mechanical ventilation. Controversy exists regarding the safety and long-term impact of these interventions. Ongoing multidisciplinary research will help define the impact of these agents and identify potential alternative therapies.
Christopher McPherson; Ruth E Grunau
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Publication Detail:
Type:  REVIEW     Date:  2013-12-17
Journal Detail:
Title:  Clinics in perinatology     Volume:  41     ISSN:  1557-9840     ISO Abbreviation:  Clin Perinatol     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-2-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  209-227     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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