| Neonatal Candida meningitis: significance of cerebrospinal fluid parameters and blood cultures. | |
| | |
MedLine Citation:
|
PMID: 17080094 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The purpose of this study was to examine the frequency of normal cerebrospinal fluid (CSF) parameters in Candida meningitis and the proportion of candidemia associated with Candida meningitis. STUDY DESIGN: We evaluated the initial lumbar puncture results from infants discharged from 150 Neonatal Intensive Care Units between 1997 and 2004. Candida meningitis was diagnosed by a positive CSF culture or positive Gram stain for yeast. We calculated two-tailed P-values using non-parametric testing, Mann-Whitney, Kruskal-Wallis or Fisher's exact tests where appropriate. RESULTS: Twenty infants had culture-positive Candida meningitis. Normal CSF parameters were found in 43% (3/7) of the infants with Candida meningitis and only 37% (7/19) of them had positive blood cultures for Candida. CONCLUSION: Normal CSF parameters do not exclude the diagnosis of neonatal Candida meningitis. The majority of infants in this cohort with Candida meningitis did not have evidence of candidemia at the time of diagnosis. |
| | |
Authors:
|
M Cohen-Wolkowiez; P B Smith; B Mangum; W J Steinbach; B D Alexander; C M Cotten; R H Clark; T J Walsh; D K Benjamin |
Related Documents
:
|
16726604 - In vitro exposure of ovine ova to (brucella abortus ). 20819964 - Cerebrospinal fluid enterovirus testing in infants 56 days or younger. 10629674 - Evaluation and management of infants with fever. 6602974 - Haemophilus influenzae type b disease after rifampin prophylaxis in a day care center: ... 1760064 - A review of newborn medicine in america: european past and guiding ideology. 19762174 - Initial nutritional management of the preterm infant. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2006-11-02 |
Journal Detail:
|
Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 27 ISSN: 0743-8346 ISO Abbreviation: J Perinatol Publication Date: 2007 Feb |
Date Detail:
|
Created Date: 2007-01-30 Completed Date: 2007-03-30 Revised Date: 2007-12-03 |
Medline Journal Info:
|
Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
|
Languages: eng Pagination: 97-100 Citation Subset: IM |
Affiliation:
|
Department of Pediatrics, Duke University, Durham, NC 27705, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Blood Glucose
/
analysis Candidiasis / blood*, cerebrospinal fluid* Female Humans Infant, Newborn Leukocyte Count Male Meningitis, Bacterial / blood*, cerebrospinal fluid*, microbiology Sepsis / cerebrospinal fluid, microbiology* |
| Grant Support | |
ID/Acronym/Agency:
|
HD044799-01/HD/NICHD NIH HHS; T32 AI052080/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Blood Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Erectile dysfunction influences the subsequent incidence of lower urinary tract symptoms and bother.
Next Document: Second trimester placental location as a predictor of an adverse pregnancy outcome.