Document Detail


Neonatal abstinence syndrome: treatment and pediatric outcomes.
MedLine Citation:
PMID:  23314720     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent rise in rates of opiate replacement therapy among pregnant women have resulted in increasing number of infants requiring treatment for neonatal abstinence syndrome (NAS). Short-term and long-term developmental outcomes associated with prenatal opiate exposure are discussed, including symptoms and severity of NAS, and early cognitive and motor delays. Maternal and infant risk factors are discussed, and include patterns of maternal substance use during pregnancy, genetic risk, polysubstance exposure pharmacological treatment for NAS and breastfeeding. The importance of characterizing corollary environmental risk factors is also considered.
Authors:
Beth A Logan; Mark S Brown; Marie J Hayes
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Clinical obstetrics and gynecology     Volume:  56     ISSN:  1532-5520     ISO Abbreviation:  Clin Obstet Gynecol     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-01     Completed Date:  2013-08-02     Revised Date:  2014-03-07    
Medline Journal Info:
Nlm Unique ID:  0070014     Medline TA:  Clin Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  186-92     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Developmental Disabilities / etiology
Female
Humans
Infant, Newborn
Methadone / therapeutic use
Narcotics / therapeutic use
Neonatal Abstinence Syndrome / etiology*,  therapy
Opiate Substitution Treatment / adverse effects*
Opioid-Related Disorders / complications*,  drug therapy
Pregnancy
Pregnancy Complications* / drug therapy
Prenatal Care
Prenatal Exposure Delayed Effects / etiology*
Severity of Illness Index
Grant Support
ID/Acronym/Agency:
NIH DA4806/DA/NIDA NIH HHS; R21 DA024806/DA/NIDA NIH HHS
Chemical
Reg. No./Substance:
0/Narcotics; UC6VBE7V1Z/Methadone
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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