| Neonatal and 5-year outcomes after birth at 30-34 weeks of gestation. | |
| | |
MedLine Citation:
|
PMID: 17601899 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To evaluate the rates of in-hospital death, neonatal complications, and 5-year outcomes of infants born at 30-34 weeks of gestation. METHODS: In nine regions of France, all 2,020 stillbirths and live births at 30, 31, and 32 weeks in 1997 and all 457 births at 33 and 34 weeks in April and October 1997 were recorded. Survivors were evaluated at 5 years of age. RESULTS: Increasing gestational age from 30 to 34 weeks was associated with progressive decreases in in-hospital mortality (from 8.1% to 0.4%) and neonatal complications (respiratory distress syndrome, 43.8% to 2.6%; maternofetal infections, 7.2% to 2.6%; and severe white matter injury, 5.5% to 1.3%). Although infants at 33 and 34 weeks of gestation rarely experienced necrotizing enterocolitis, bronchopulmonary dysplasia, or nosocomial infections, they still required endotracheal ventilation, antibiotics, or parenteral nutrition. At 5 years of age, older gestational age was associated with significant decreases in rates of cerebral palsy (6.3% at 30 weeks and 0.7% at 34 weeks) and mild to severe cognitive impairments (35.3% at 30 weeks and 23.9% at 34 weeks). In singletons, preterm rupture of membranes or preterm labor carried an increased risk of cerebral palsy but not of cognitive impairment. CONCLUSION: Neonates born at 30-34 weeks experienced substantial morbidity and often required admission to neonatal intensive care units. These outcomes suggest that prolonging pregnancies beyond 34 weeks may be desirable whenever possible. Infants born at 30-34 weeks should be carefully monitored to ensure prompt detection and management of neurodevelopmental impairment. |
| | |
Authors:
|
Stéphane Marret; Pierre-Yves Ancel; Loïc Marpeau; Laetitia Marchand; Véronique Pierrat; Béatrice Larroque; Laurence Foix-L'Hélias; Gérard Thiriez; Jeanne Fresson; Corinne Alberge; Jean-Christophe Rozé; Jacqueline Matis; Gérard Bréart; Monique Kaminski; |
Related Documents
:
|
8318809 - Subependymal pseudocysts: ultrasound diagnosis and findings at follow-up. 22622499 - Early initiation of peritoneal dialysis in neonates and infants with acute kidney injur... 9131309 - Antenatal and delivery risk factors simultaneously associated with neonatal death and c... 11827899 - Effects of cognitive, motor, and sensory disabilities on survival in cerebral palsy. 15113629 - Association of cord blood cytokines with prematurity and cerebral palsy. 19773459 - Pathological evidence of vacuolar myelinopathy in a child following vigabatrin administ... 3706239 - Postponed neonatal death in the premature infant. 22240109 - An evidence-based catheter bundle alters central venous catheter strategy in newborn in... 7178669 - Respiratory compliance of newborns after birth and its prognostic value for the course ... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Obstetrics and gynecology Volume: 110 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2007 Jul |
Date Detail:
|
Created Date: 2007-07-02 Completed Date: 2007-07-31 Revised Date: 2009-10-26 |
Medline Journal Info:
|
Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 72-80 Citation Subset: AIM; IM |
Affiliation:
|
Department of Neonatal Medicine, Rouen University Hospital and Inserm Avenir Research Group, Institute for Biomedical Research, University of Rouen, Rouen, France. stephane.marret@chu-rouen.fr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cerebral Palsy
/
epidemiology* Child, Preschool Cognition Disorders / epidemiology* Cohort Studies Female Follow-Up Studies France / epidemiology Gestational Age* Humans Incidence Infant Mortality Infant, Newborn Intensive Care, Neonatal / utilization Male Patient Admission / statistics & numerical data Pregnancy Pregnancy Trimester, Third Premature Birth* Retrospective Studies Stillbirth / epidemiology |
| Comments/Corrections | |
Comment In:
|
Obstet Gynecol. 2007 Nov;110(5):1171-2; author reply 1172
[PMID:
17978138
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Uterine compression sutures for postpartum hemorrhage: efficacy, morbidity, and subsequent pregnancy...
Next Document: Influence of an "opt-out" test strategy and patient factors on human immunodeficiency virus screenin...