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Neoadjuvant Therapy for Potentially Resectable Pancreatic Cancer: An Emerging Paradigm?
MedLine Citation:
PMID:  23325567     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Although neoadjuvant chemoradiotherapy has been tested for more than two decades and can be safely delivered to patients with non-metastatic pancreatic cancer, no randomised trials have been reported until now. Here we provide an overview of the first randomised trial in patients with potentially resectable cancer and of the latest developments in neoadjuvant therapy for this group of patients. It is necessary to continue to perform clinical trials in this field to accurately identify the effect on survival and quality of life in patients with potentially resectable, borderline resectable and unresectable pancreatic cancer. Aspects of imaging for restaging and clinical prognostic factors are also discussed given they will be useful instruments for future trials.
Authors:
Thomas B Brunner
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-17
Journal Detail:
Title:  Current oncology reports     Volume:  -     ISSN:  1534-6269     ISO Abbreviation:  Curr Oncol Rep     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888967     Medline TA:  Curr Oncol Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Radiation Oncology, Freiburg University, Robert-Koch-Str. 3, 79106, Freiburg, Germany, thomas.brunner@uniklinik-freiburg.de.
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