Document Detail

Neisseria sicca Endocarditis Requiring Mitral Valve Replacement in a Previously Healthy Adolescent.
MedLine Citation:
PMID:  21975499     Owner:  NLM     Status:  In-Data-Review    
Infective endocarditis due to Neisseria sicca, a normal inhabitant of the upper respiratory tract, is rarely reported but associated with embolic phenomena and large vegetations often requiring surgical intervention. We report a previously healthy 12-year-old girl who presented with prolonged fever and altered mental status. The patient developed rapidly progressive respiratory insufficiency and cardiovascular instability, and echocardiography demonstrated a large vegetation on the mitral valve. She developed worsening mitral regurgitation with resultant pulmonary hemorrhage and underwent mitral valve replacement. Her blood culture was positive for N. sicca. This infection should be considered in patients with prolonged high fever and multiorgan dysfunction. Despite a typically severe course, reported mortality is low.
Paul L Aronson; Kyle A Nelson; Laura Mercer-Rosa; Aaron Donoghue
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric emergency care     Volume:  27     ISSN:  1535-1815     ISO Abbreviation:  Pediatr Emerg Care     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8507560     Medline TA:  Pediatr Emerg Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  959-62     Citation Subset:  IM    
From the *Division of Emergency Medicine, The Children's Hospital of Philadelphia; and †Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA; ‡Division of Emergency Medicine, Children's Hospital Boston; and §Department of Pediatrics, Harvard University School of Medicine, Boston, MA; and ∥Division of Cardiology, and ¶Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA.
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