Document Detail

Neisseria lactamica meningitis following skull trauma.
MedLine Citation:
PMID:  2041952     Owner:  NLM     Status:  MEDLINE    
A woman developed meningitis due to Neisseria lactamica in association with a cribriform plate fracture. Cerebrospinal fluid antigen tests for Neisseria meningitidis were negative. The patient recovered with intravenous penicillin therapy. N. lactamica can be rapidly distinguished from N. meningitidis by the hydrolysis of ONPG (o-nitrophenyl-beta-D-galactopyranoside). In contrast to N. meningitidis and Neisseria gonorrhoeae, N. lactamica lacks virulence properties. As 100% of N. lactamica strains are susceptible to penicillin and all three previously described patients with N. lactamica meningitis have recovered with penicillin treatment, the reason for distinguishing the organisms in this context is primarily to prevent unnecessary anxiety and prophylaxis among contacts.
D W Denning; S S Gill
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Reviews of infectious diseases     Volume:  13     ISSN:  0162-0886     ISO Abbreviation:  Rev. Infect. Dis.     Publication Date:    1991 Mar-Apr
Date Detail:
Created Date:  1991-07-08     Completed Date:  1991-07-08     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7905878     Medline TA:  Rev Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  216-8     Citation Subset:  IM    
Department of Medicine, Santa Clara Valley Medical Center, San Jose, California.
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MeSH Terms
Ceftizoxime / therapeutic use
Drug Therapy, Combination / therapeutic use
Ethmoid Bone / injuries*,  surgery
Meningitis / drug therapy,  etiology*,  microbiology
Middle Aged
Neisseria / drug effects,  isolation & purification*
Penicillins / pharmacology,  therapeutic use
Skull Fractures / complications*,  surgery
Reg. No./Substance:
0/Penicillins; 68401-81-0/Ceftizoxime

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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