Document Detail

Neighborhood disadvantage as a risk factor for pediatric obstructive sleep apnea.
MedLine Citation:
PMID:  16939744     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Low socioeconomic status (SES) is associated with a range of health outcomes. Our objective was to study the relationship between residence in a neighborhood of severe socioeconomic disadvantage and childhood obstructive sleep apnea (OSA). STUDY DESIGN: Cross-sectional analysis of 843 (49% female, 36% African-American) children 8 to 11 years of age from a community-based cohort. Data on neighborhood conditions were obtained from the 2000 US Census. The main outcome measure was OSA, defined as an obstructive apnea hypopnea index >5 events per hour or an obstructive apnea index >1 event per hour. RESULTS: Residence in a neighborhood of severe socioeconomic disadvantage was significantly associated with OSA after adjusting for effects of previously established risk factors: premature birth, obesity, and African-American ethnicity (OR = 3.44, 95% CI = 1.53-7.75). Secondary analyses showed that neighborhood disadvantage remained significantly associated with OSA: (1) in the African-American subgroup, after controlling for effects of prematurity and obesity; and (2) after controlling for indicators of household-level SES or other health characteristics. CONCLUSIONS: Childhood OSA is associated with low SES as measured by an index describing severe neighborhood disadvantage, emphasizing the potential importance of environmental factors, particularly those associated with neighborhood distress, as risk factors for OSA.
James C Spilsbury; Amy Storfer-Isser; H Lester Kirchner; Lisa Nelson; Carol L Rosen; Dennis Drotar; Susan Redline
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  149     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-30     Completed Date:  2006-10-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  342-7     Citation Subset:  AIM; IM    
Mental Health Services Inc., 3740 Euclid Avenue, Cleveland, OH 44115, USA.
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MeSH Terms
Cohort Studies
Cross-Sectional Studies
Poverty Areas*
Residence Characteristics*
Risk Factors
Sleep Apnea, Obstructive / epidemiology*
Social Class*
Grant Support
5T32 HD 041923/HD/NICHD NIH HHS; K23 HL 04426/HL/NHLBI NIH HHS; M01 RR 00080/RR/NCRR NIH HHS; R01 070916//PHS HHS; R01 HL 60957/HL/NHLBI NIH HHS; R01 NR 02707/NR/NINR NIH HHS
Comment In:
J Pediatr. 2006 Sep;149(3):293-4   [PMID:  16939735 ]

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