Document Detail

Negative silver staining in A-T and satellite DNA-rich regions of human chromosomes.
MedLine Citation:
PMID:  60207     Owner:  NLM     Status:  MEDLINE    
Human metaphase chromosomes were stained with silver following a pretreatment with a heated alkaline solution. The most conspicuous feature of the stained metaphases was the omission of silver staining in the secondary constrictions of chromosomes 1,9 and 16, and on the distal Yq. Our evidence indicates that the negative silver binding is due to the preferential removal or alteration of non-histone proteins associated with these regions. The cytochemical significance of these findings is discussed.
W M Howell; T E Denton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chromosoma     Volume:  57     ISSN:  0009-5915     ISO Abbreviation:  Chromosoma     Publication Date:  1976 Aug 
Date Detail:
Created Date:  1976-11-01     Completed Date:  1976-11-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985138R     Medline TA:  Chromosoma     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  165-9     Citation Subset:  IM    
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MeSH Terms
Adenine Nucleotides / analysis*
Chromosomes / analysis*
Chromosomes, Human, 1-3
Chromosomes, Human, 16-18
Chromosomes, Human, 6-12 and X
DNA / analysis*
DNA, Satellite / analysis*
Sex Chromosomes / analysis
Staining and Labeling
Thymine Nucleotides / analysis*
Reg. No./Substance:
0/Adenine Nucleotides; 0/DNA, Satellite; 0/Thymine Nucleotides; 7440-22-4/Silver; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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