| Negative-pressure wound therapy I: the paradox of negative-pressure wound therapy. | |
| | |
MedLine Citation:
|
PMID: 19182617 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Does negative-pressure wound therapy reduce or increase the pressure of wound tissues? This seemingly obvious question has never been addressed by a study on living tissues. The aim of this study was to evaluate the nature of tissue pressure changes in relation to negative-pressure wound therapy. METHODS: Three negative-pressure wound therapy dressing configurations were evaluated-circumferential, noncircumferential, and those within a cavity-on 15 human wounds, with five wounds in each category. Tissue pressure changes were recorded (using a strain gauge sensor) for each 75-mmHg increment in suction, up to -450 mmHg. In the circumferential and noncircumferential groups, tissue pressure was also measured over a 48-hour period at a set suction pressure of -125 mmHg (n = 10). RESULTS: In all three groups, mean tissue pressure increased proportionately to the amount of suction applied (p < 0.0005). Mean tissue pressure increments resulting from the circumferential dressings were significantly higher than those resulting from the noncircumferential (p < 0.0005) or cavity group (p < 0.0005); however, there was no significant difference between the latter two groups (p = 0.269). Over the 48-hour period, there was a significant mean reduction in the (increased) tissue pressure (p < 0.04 for circumferential and p < 0.0005 for noncircumferential), but in only three of 10 cases did this reduce to pressures less than those before dressing application. CONCLUSIONS: Negative-pressure wound therapy increases tissue pressure proportionately to the amount of suction, although this becomes less pronounced over 48 hours. This suggests that negative-pressure wound therapy dressings should be used with caution on tissues with compromised perfusion, particularly when they are circumferential. |
| | |
Authors:
|
Nicolas Kairinos; Michael Solomons; Donald A Hudson |
Related Documents
:
|
10211847 - Fibroblast responses to variation in soft tissue mobilization pressure. 7630027 - Thermal conditions in the bathroom in winter and summer, and physiological responses of... 14726737 - The 2003 carl a moyer award: real-time metabolic monitors, ischemia-reperfusion, titrat... 2095177 - The effects of an abrasive agent on normal skin and on photoaged skin in comparison wit... 14643577 - Direct comparison of the effects of valsartan and amlodipine on renal hemodynamics in h... 10168357 - Methods to objectify reversibility of glaucomatous cupping. |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Plastic and reconstructive surgery Volume: 123 ISSN: 1529-4242 ISO Abbreviation: Plast. Reconstr. Surg. Publication Date: 2009 Feb |
Date Detail:
|
Created Date: 2009-02-02 Completed Date: 2009-03-02 Revised Date: 2011-02-16 |
Medline Journal Info:
|
Nlm Unique ID: 1306050 Medline TA: Plast Reconstr Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 589-98; discussion 599-600 Citation Subset: AIM; IM |
Affiliation:
|
Department of Plastic and Reconstructive Surgery and the Martin Singer Hand Unit, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa. nickykairinos@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Hand Injuries
/
therapy Humans Negative-Pressure Wound Therapy / contraindications, methods* Pressure Skin / injuries* Stress, Mechanical Thigh Transducers, Pressure* Wound Healing Wounds and Injuries / therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The free gracilis perforator flap: anatomical study and clinical refinements of a new perforator fla...
Next Document: Negative-pressure wound therapy II: negative-pressure wound therapy and increased perfusion. Just an...