Document Detail

Negative diastolic pressure in the intact canine right ventricle. Evidence of diastolic suction.
MedLine Citation:
PMID:  7237688     Owner:  NLM     Status:  MEDLINE    
To determine whether the canine right ventricle (RV) can develop a negative diastolic pressure indicative of suction, RV pressure was measured in 15 dogs, with catheter-tip micromanometers. Six dogs were studied only with the chest closed. In these dogs, intrapleural pressure was measured medially (near the heart) in four and laterally in two. In nine dogs, RV pressure was evaluated with the chest closed and after the chest had been opened. In all dogs, with the chest closed, minimal RV diastolic pressure during expiration was negative, -4.8 +/- 0.3 mm Hg. The lowest diastolic pressures occurred during early diastole. Intrapleural pressure during expiration was never this low. Intrapleural pressure measured medially in four dogs was positive during expiration (1.0 +/- 0.6 mm Hg). In the two dogs which it was measured in the lateral pleural space, it was somewhat negative during expiration (-2.5 and -1.3 mm Hg, respectively). After the chest had been opened (nine dogs) minimal RV pressure during early diastole was negative in six dogs and positive in three (range: -1.8 to 0.8 mm Hg). These results indicate that the negative RV diastolic pressure during expiration did not result from a negative intrathoracic pressure. It appears that the RV during early diastole can create a sucking effect which may contribute to the filling process.
H N Sabbah; P D Stein
Related Documents :
8727028 - Dynamic right and left ventricular interactions in the rabbit: simultaneous measurement...
6985848 - Quantification of aortic valvular regurgitation in dogs by nuclear imaging.
6349388 - Cardiovascular changes from expiration to inspiration during ippv.
16256218 - The determinants of right ventricular function in patients with atrial septal defect.
6395138 - Treatment with prostacyclin of various forms of spontaneous angina pectoris not respond...
12422578 - Blood pressure and heart rate during an episode of unstable angina as predictors of in-...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Circulation research     Volume:  49     ISSN:  0009-7330     ISO Abbreviation:  Circ. Res.     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-08-27     Completed Date:  1981-08-27     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0047103     Medline TA:  Circ Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  108-13     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Myocardial Contraction*
Thorax / physiology
Ventricular Function*
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The effects of cortisone therapy on lung macrophage host defense function and glucose metabolism.
Next Document:  Muscle extract infusion in rabbits. A new experimental model of the crush syndrome.