| Needle with a novel attachment versus conventional screw-thread needles: a preference and usability test among adults with diabetes and impaired manual dexterity. | |
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MedLine Citation:
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PMID: 21406015 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: NovoTwist(®) (Novo Nordisk A/S, Bagsværd, Denmark) is an insulin pen needle that features a novel attachment and detachment system. The aim of this test was to assess overall preference and handling of NovoTwist compared with conventional screw-thread needles in people with type 1 or type 2 diabetes. METHODS: One hundred twenty adults with type 1 or type 2 diabetes and manual dexterity dysfunction who were currently self-injecting with an insulin pen were included in this open-label, randomized, crossover test. Participants were stratified according to the impact that manual dexterity problems had on their ability to inject insulin (1 = no effect at all; 4 = a lot), and those rated as 1 were excluded from subanalyses because of low numbers. Following instruction, participants attached the needle to Next Generation FlexPen(®) (Novo Nordisk A/S), made an injection into a foam cushion, and detached the needle; this process was repeated three times with NovoTwist and the participant's current screw-thread needle (or NovoFine(®) [Novo Nordisk A/S]) in a random order. Responses to questions on user experience with each needle were subsequently recorded on a 6-point rating scale (1 = very difficult; 6 = very easy). RESULTS: Significantly more respondents had a preference for NovoTwist (79%) compared with the conventional screw-thread needles (21%, P < 0.001). Significantly more respondents preferred NovoTwist for both ease of attachment (80%, P < 0.001) and ease of detachment (74%, P < 0.001). Most respondents found NovoTwist the most appropriate needle for performing everyday injections (71%, P < 0.001). CONCLUSIONS: Such preference by patients has a positive impact on the treatment of diabetes as NovoTwist may alleviate the burden of performing everyday injections through its ease of use. |
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Authors:
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Birtha Hansen; Søren K Lilleøre; Gitte Ter-Borch |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2011-03-15 |
Journal Detail:
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Title: Diabetes technology & therapeutics Volume: 13 ISSN: 1557-8593 ISO Abbreviation: Diabetes Technol. Ther. Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-28 Completed Date: 2011-08-24 Revised Date: 2011-08-25 |
Medline Journal Info:
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Nlm Unique ID: 100889084 Medline TA: Diabetes Technol Ther Country: United States |
Other Details:
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Languages: eng Pagination: 579-85 Citation Subset: IM |
Affiliation:
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Department of Medical Endocrinology, Aarhus University Hospital, Aarhus, Denmark. BH@KI.AU.DK |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cross-Over Studies Diabetes Mellitus / drug therapy*, physiopathology, psychology Drug Delivery Systems / adverse effects, instrumentation*, psychology Equipment Design / psychology Female Great Britain Humans Injections, Subcutaneous Insulin / administration & dosage*, therapeutic use Italy Male Materials Testing Middle Aged Needles* / adverse effects Patient Preference* Self Administration / psychology Self-Help Devices* |
| Chemical | |
Reg. No./Substance:
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11061-68-0/Insulin |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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