| Need for Standardization of 18F-FDG PET/CT for Treatment Response Assessments. | |
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MedLine Citation:
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PMID: 22144561 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Many factors affect standardized uptake values (SUVs) in (18)F-FDG PET/CT. The use of the SUV from a single PET scan in multicenter studies requires the standardization of (18)F-FDG PET/CT procedures. In the context of treatment response assessments (repeated PET scans), many factors may seem to have minor effects on percentage changes in SUVs, provided that imaging procedures are executed in a consistent manner for each subject. However, the use of (18)F-FDG PET/CT in a nonstandardized manner will result in unknown biases and reproducibilities of SUVs and SUV-based response measures. This article provides an overview of the need for standardization in relation to the specific use of SUVs and SUV changes in studies of treatment response assessments. |
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Authors:
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Ronald Boellaard |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of nuclear medicine : official publication, Society of Nuclear Medicine Volume: 52 Suppl 2 ISSN: 1535-5667 ISO Abbreviation: J. Nucl. Med. Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0217410 Medline TA: J Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 93S-100S Citation Subset: IM |
Affiliation:
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VU University Medical Center, Amsterdam, The Netherlands. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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