Document Detail


Necrotizing lesions in Sjögren's syndrome. I. An immunofluorescent study.
MedLine Citation:
PMID:  7424196     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Necrotizing lesions were found in labial salivary glands from patients bearing Sjögren's syndrome associated to rheumatoid arthritis, systemic sclerosis and systemic lupus erythematosus. In small and well circumscribed areas, parenchyma necrosis was accompanied by oedema, polymorphs and plasma cells. Immunoglobulins and complement deposition was demonstrated in serial sections. The immunological basis of these lesions and their significance in Sjögren's syndrome are discussed.
Authors:
H Friedman; M Egami; V Kilmar
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Zeitschrift für Rheumatologie     Volume:  39     ISSN:  0340-1855     ISO Abbreviation:  Z Rheumatol     Publication Date:    1980 Jan-Feb
Date Detail:
Created Date:  1980-12-16     Completed Date:  1980-12-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0414162     Medline TA:  Z Rheumatol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  28-32     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Autoimmune Diseases / immunology
Complement C3 / analysis
Humans
Immunoglobulins / analysis
Necrosis
Salivary Glands / pathology*
Sjogren's Syndrome / immunology,  pathology*
Chemical
Reg. No./Substance:
0/Complement C3; 0/Immunoglobulins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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