Document Detail

Necrotizing fasciitis after peritonsillar abscess in an immunocompetent patient.
MedLine Citation:
PMID:  10748857     Owner:  NLM     Status:  MEDLINE    
Cervical necrotizing fasciitis (CNF) is a rapidly progressive, severe bacterial infection of the fascial planes of the head and neck. Group A beta haemolytic Streptococcus spp. (GABHS), Staphylococcus spp., or obligatory anaerobic bacteria are the most common causative pathogens. The disease usually results from a dental source or facial trauma. Extensive fascial necrosis and severe systemic toxicity are common manifestations of CNF. Review of the literature reveals only seven such cases, with four successful outcomes. The authors present the case of a 50-year-old immunocompetent female with CNF arising from a peritonsillar abscess. Intravenous immunoglobulins in conjunction with surgery and antibiotics were used successfully. The authors also suggest the importance of the early diagnosis, aggressive surgical debridement, broad-spectrum antibiotics, and possible usefulness of the intravenous immunoglobulins in the treatment of CNF, especially when the disease is associated with toxic shock syndrome.
N Skitarelić; R Mladina; Z Matulić; M Kovacić
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  113     ISSN:  0022-2151     ISO Abbreviation:  J Laryngol Otol     Publication Date:  1999 Aug 
Date Detail:
Created Date:  2000-04-25     Completed Date:  2000-04-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  759-61     Citation Subset:  AIM; IM    
Department Otolaryngology-Head and Neck Surgery, General Hospital, Zadar, Croatia.
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MeSH Terms
Fasciitis, Necrotizing / etiology*,  surgery,  therapy
Immunoglobulins, Intravenous / therapeutic use
Middle Aged
Opportunistic Infections / complications
Peritonsillar Abscess / complications*
Staphylococcal Infections / complications
Streptococcal Infections / complications
Reg. No./Substance:
0/Immunoglobulins, Intravenous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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