Document Detail

Necrotizing enterocolitis requiring surgery: outcomes by intestinal location of disease in 4371 infants.
MedLine Citation:
PMID:  21843711     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: The objective of this study was to determine whether the outcomes of infants with surgically managed necrotizing enterocolitis (NEC) differ according to whether the location of NEC is in the small bowel, large bowel, or both.
STUDY DESIGN: A retrospective analysis was performed using the Healthcare Cost and Utilization Project Nationwide Inpatient Sample and Kids' Inpatient Database. A total of 5374 infants identified as having undergone surgical management of NEC were stratified by location of bowel affected as small bowel (SB) only, large bowel (LB) only, or both small and large bowel (SB&LB). The type of surgical operation performed was used as a proxy for the location of bowel affected.
RESULTS: Of the 5374 infants with a diagnosis of NEC, 4371 had an operation that allowed for stratification by location. The LB group (n = 963) fared the best in all outcomes. The SB group (n = 2126) had the longest length of stay and highest total hospital charges, and mortality was comparable with that of the SB&LB group (n = 1282).
CONCLUSIONS: Mortality, length of stay, and total hospital charges varied according to location of bowel affected by NEC.
Yiyi Zhang; Gezzer Ortega; Melissa Camp; Hayley Osen; David C Chang; Fizan Abdullah
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  46     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1475-81     Citation Subset:  IM    
Copyright Information:
Copyright © 2011. Published by Elsevier Inc.
Department of Epidemiology, Johns Hopkins University School of Public Health, Baltimore, MD 21205, USA; Center for Pediatric Surgical Clinical Trials & Outcomes Research, Division of Pediatric Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
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