Document Detail


Necrotizing enterocolitis: improving survival within a single facility.
MedLine Citation:
PMID:  2772678     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Necrotizing enterocolitis (NEC), a disease associated with prematurity, carries a significant morbidity and mortality. This study was designed to evaluate our progress in dealing with NEC both medically and surgically in a single large neonatal intensive care unit (NICU). We also sought to confirm the relation of birth weight and particular indications for operation to outcome. Over 6 1/2 years, there were 7,807 admissions to a large NICU. Though there has been a steady increase in total admissions, especially of infants weighing less than 1,000 gm, survival has improved significantly in all groups (mean 89.1%). NEC occurred in 358 infants (4.6%), and 115 (32%) required surgical intervention. Infants weighing between 751 and 1,000 gm had the highest incidence of NEC. There has been a significant decrease in the mortality of both medically and surgically treated infants with NEC; in both cases, this decrease is weight-dependent. We found that using erythema and edema of the abdominal wall and a fixed-loop roentgenographic pattern as early indicators of necrotic bowel significantly improves survival in surgically treated infants.
Authors:
T L Black; M G Carr; S B Korones
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  82     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1989-10-12     Completed Date:  1989-10-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1103-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Pediatric Surgery, LeBonheur Children's Medical Center, Memphis.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Birth Weight
Combined Modality Therapy
Emergencies
Enterocolitis, Pseudomembranous / epidemiology,  mortality*,  surgery,  therapy
Evaluation Studies as Topic
Hospitals, District
Humans
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature, Diseases / epidemiology,  mortality*,  surgery,  therapy
Intensive Care Units, Neonatal
Retrospective Studies
Tennessee

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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