| Necrotizing enterocolitis: improving survival within a single facility. | |
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MedLine Citation:
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PMID: 2772678 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Necrotizing enterocolitis (NEC), a disease associated with prematurity, carries a significant morbidity and mortality. This study was designed to evaluate our progress in dealing with NEC both medically and surgically in a single large neonatal intensive care unit (NICU). We also sought to confirm the relation of birth weight and particular indications for operation to outcome. Over 6 1/2 years, there were 7,807 admissions to a large NICU. Though there has been a steady increase in total admissions, especially of infants weighing less than 1,000 gm, survival has improved significantly in all groups (mean 89.1%). NEC occurred in 358 infants (4.6%), and 115 (32%) required surgical intervention. Infants weighing between 751 and 1,000 gm had the highest incidence of NEC. There has been a significant decrease in the mortality of both medically and surgically treated infants with NEC; in both cases, this decrease is weight-dependent. We found that using erythema and edema of the abdominal wall and a fixed-loop roentgenographic pattern as early indicators of necrotic bowel significantly improves survival in surgically treated infants. |
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Authors:
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T L Black; M G Carr; S B Korones |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Southern medical journal Volume: 82 ISSN: 0038-4348 ISO Abbreviation: South. Med. J. Publication Date: 1989 Sep |
Date Detail:
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Created Date: 1989-10-12 Completed Date: 1989-10-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404522 Medline TA: South Med J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1103-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatric Surgery, LeBonheur Children's Medical Center, Memphis. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Birth Weight Combined Modality Therapy Emergencies Enterocolitis, Pseudomembranous / epidemiology, mortality*, surgery, therapy Evaluation Studies as Topic Hospitals, District Humans Infant, Low Birth Weight Infant, Newborn Infant, Premature, Diseases / epidemiology, mortality*, surgery, therapy Intensive Care Units, Neonatal Retrospective Studies Tennessee |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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