| Necrotic leiomyoma and gram-negative sepsis eight weeks after uterine artery embolization. | |
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MedLine Citation:
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PMID: 15516437 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Uterine artery embolization for symptomatic leiomyomata is generally safe, but rare life-threatening complications, including sepsis, can result. CASE: A 39-year-old woman with primary antiphospholipid syndrome, who was on chronic warfarin therapy, underwent uterine artery embolization for severe menorrhagia and a 12-cm intracavitary leiomyoma. Eight weeks postembolization, the patient, who had been essentially asymptomatic, presented in septic shock from gram-negative anaerobic bacteria. She underwent hysterectomy and bilateral salpingo-oophorectomy for a large infarcted necrotic leiomyoma and partial uterine necrosis. The patient's 8-day hospitalization required extended care in the intensive care unit and blood transfusion and resulted in surgical menopause in a patient who is not a candidate for hormone therapy. CONCLUSION: Uterine artery embolization is a procedure not without significant risks. From published case reports, it appears that patients most at risk for severe infection of an infarcted leiomyoma after this procedure are those with a large dominant leiomyoma. |
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Authors:
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Matthew Aungst; Mark Wilson; Karen Vournas; Sarah McCarthy |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 104 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2004 Nov |
Date Detail:
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Created Date: 2004-11-01 Completed Date: 2005-01-04 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 1161-4 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, David Grant Medical Center, Travis Air Force Base, California, USA. Mathew.aungst@60mdg.travis.af.mil |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Bacterial Agents Combined Modality Therapy Drug Therapy, Combination / therapeutic use Embolization, Therapeutic / adverse effects*, methods Female Follow-Up Studies Gram-Negative Bacterial Infections / diagnosis, etiology*, therapy Humans Hysterectomy / methods Infusions, Intravenous Leiomyoma / pathology, therapy* Necrosis / pathology Ovariectomy / methods Severity of Illness Index Shock, Septic / diagnosis, etiology*, therapy Tomography, X-Ray Computed Treatment Outcome Uterine Neoplasms / pathology, therapy* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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