Document Detail

Necrotic leiomyoma and gram-negative sepsis eight weeks after uterine artery embolization.
MedLine Citation:
PMID:  15516437     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Uterine artery embolization for symptomatic leiomyomata is generally safe, but rare life-threatening complications, including sepsis, can result. CASE: A 39-year-old woman with primary antiphospholipid syndrome, who was on chronic warfarin therapy, underwent uterine artery embolization for severe menorrhagia and a 12-cm intracavitary leiomyoma. Eight weeks postembolization, the patient, who had been essentially asymptomatic, presented in septic shock from gram-negative anaerobic bacteria. She underwent hysterectomy and bilateral salpingo-oophorectomy for a large infarcted necrotic leiomyoma and partial uterine necrosis. The patient's 8-day hospitalization required extended care in the intensive care unit and blood transfusion and resulted in surgical menopause in a patient who is not a candidate for hormone therapy. CONCLUSION: Uterine artery embolization is a procedure not without significant risks. From published case reports, it appears that patients most at risk for severe infection of an infarcted leiomyoma after this procedure are those with a large dominant leiomyoma.
Matthew Aungst; Mark Wilson; Karen Vournas; Sarah McCarthy
Related Documents :
19007597 - A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ...
17693437 - What cardioversion protocol for ventricular fibrillation should be followed for patient...
20331487 - Mechanical circulatory support for ami and cardiogenic shock.
15009877 - Inappropriate icd therapy due to proarrhythmic icd shocks and hyperpolarization.
23141857 - Comorbidity significantly affects clinical outcome after cardiac resynchronization ther...
16520267 - Immediate functional effects of left ventricular reduction: a doppler echocardiographic...
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  104     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-11-01     Completed Date:  2005-01-04     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1161-4     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, David Grant Medical Center, Travis Air Force Base, California, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anti-Bacterial Agents
Combined Modality Therapy
Drug Therapy, Combination / therapeutic use
Embolization, Therapeutic / adverse effects*,  methods
Follow-Up Studies
Gram-Negative Bacterial Infections / diagnosis,  etiology*,  therapy
Hysterectomy / methods
Infusions, Intravenous
Leiomyoma / pathology,  therapy*
Necrosis / pathology
Ovariectomy / methods
Severity of Illness Index
Shock, Septic / diagnosis,  etiology*,  therapy
Tomography, X-Ray Computed
Treatment Outcome
Uterine Neoplasms / pathology,  therapy*
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Buttock necrosis after uterine artery embolization.
Next Document:  Rectovaginal fistula repair using a porcine dermal graft.