Document Detail

Necrobiotic xanthogranuloma of the parotid gland.
MedLine Citation:
PMID:  19825226     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To highlight the first reported case of necrobiotic xanthogranuloma of the parotid gland. We also review the clinical presentations and treatments for this rare condition. METHOD: Case report and review of necrobiotic xanthogranuloma. RESULTS: A 48-year-old man presented with a right parotid mass. Fine needle aspiration cytology was suggestive of Warthin's tumour, for which the patient underwent a subtotal parotidectomy. The final histopathological diagnosis was necrobiotic xanthogranuloma. CONCLUSIONS: Necrobiotic xanthogranuloma may clinically mimic commoner tumours such as Warthin's tumour. Once diagnosed, the clinician should be wary of extracutaneous manifestations and paraproteinaemias. Because of the variability of presentation, there is no consensus on the best treatment for necrobiotic xanthogranuloma, which may include surgery, chemotherapy, interferon, plasmapheresis and radiation therapy.
A Zainal; M Y Razif; M Makhashen; M Swaminathan; A Mazita
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-10-14
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  124     ISSN:  1748-5460     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-28     Completed Date:  2010-08-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  England    
Other Details:
Languages:  eng     Pagination:  569-71     Citation Subset:  AIM; IM    
Department of Otorhinolaryngology - Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
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MeSH Terms
Granuloma / pathology*,  surgery
Middle Aged
Parotid Diseases / pathology*,  surgery
Xanthomatosis / pathology*,  surgery

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