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Neck circumference is correlated with triglycerides and inversely related with HDL-cholesterol beyond BMI and waist circumference.
MedLine Citation:
PMID:  23135790     Owner:  NLM     Status:  Publisher    
BACKGROUND: Neck circumference, beyond a measure of obesity, is a unique fat depot with increasing significance. This study aimed to investigate the association between neck circumference and biomarkers, indicators of cardiovascular risk. METHODS: During 2009, 490 volunteers (46 ± 16 years, 40% males) were consecutively enrolled to the study (participation rate 85%). Biochemical analyses were performed through established procedures, after 12 h fasting and glucose, total cholesterol, HDL- and LDL-cholesterol, triglycerides, cystatin C, uric acid and hs-CRP were measured. Anthropometric, lifestyle and dietary characteristics were also recorded to account for potential confounders. Additive linear and logistic regression models were used to evaluate the association between neck circumference and biomarkers of cardiometabolic risk. RESULTS: A positive association between neck circumference and systolic and diastolic blood pressure, glucose, triglycerides, uric acid and hs-CRP and a negative association with HDL-cholesterol was revealed (all p's < 0.05); models adjusted for age, gender, years of school, smoking, physical activity status, MedDietScore and alcohol intake. The relationship between neck circumference and HDL-cholesterol, glucose, triglycerides and uric acid remained significant when models were further stratified by BMI class and abnormal waist circumference. CONCLUSION: Neck circumference was found to be a powerful indicator of atherogenic dyslipidemia above and beyond central obesity indicators. Copyright © 2012 John Wiley & Sons, Ltd.
Natalia G Vallianou; Angelos A Evangelopoulos; Vassiliki Bountziouka; Evangelos D Vogiatzakis; Maria S Bonou; John Barbetseas; Petros C Avgerinos; Demosthenes B Panagiotakos
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-8
Journal Detail:
Title:  Diabetes/metabolism research and reviews     Volume:  -     ISSN:  1520-7560     ISO Abbreviation:  Diabetes Metab. Res. Rev.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883450     Medline TA:  Diabetes Metab Res Rev     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 John Wiley & Sons, Ltd.
Polykliniki General Hospital, Athens, Greece.
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